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Changes in the organization of membranous structures in the amphibian oocyte cortex were studied during the process of progesterone-induced meiotic resumption. Progesterone treatment of Xenopus laevis oocytes induced short term and longer term changes in the cortical membranes. In the short term, progesterone induced a burst of endocytosis mediated through coated pits and coated vesicles. Immuno-electron-microscopic localization of progesterone suggested that the progesterone receptor, bound to its ligand, is endocytosed during progesterone-induced endocytosis. Also demonstrated was the existence of a cisternal membrane network, referred to as the primordial cortical endoplasmic reticulum, which surrounds portions of the cortical granules in oocytes. The primordial cortical endoplasmic reticulum is more highly developed in the animal hemisphere than the vegetal hemisphere. Over the long term, during the meiotic resumption, more membrane is recruited into this network to form the cortical endoplasmic reticulum observed by others in the metaphase II egg. This evidence demonstrates that the cortex serves as a site for dynamic changes in membrane organization and that the most extensive changes occur in the animal hemisphere. These data support previous observations that the animal hemisphere is better structured for sperm penetration than is the vegetal hemisphere.
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2007258
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Bement,
Protein kinase C acts downstream of calcium at entry into the first mitotic interphase of Xenopus laevis.
1990, Pubmed,
Xenbase
Bement,
Protein kinase C acts downstream of calcium at entry into the first mitotic interphase of Xenopus laevis.
1990,
Pubmed
,
Xenbase
Bement,
Transformation of the amphibian oocyte into the egg: structural and biochemical events.
1990,
Pubmed
,
Xenbase
Bement,
Intracellular signals trigger ultrastructural events characteristic of meiotic maturation in oocytes of Xenopus laevis.
1989,
Pubmed
,
Xenbase
Bement,
Activators of protein kinase C trigger cortical granule exocytosis, cortical contraction, and cleavage furrow formation in Xenopus laevis oocytes and eggs.
1989,
Pubmed
,
Xenbase
Bluemink,
Cortical wound healing in the amphibian egg: an electron microscopical study.
1972,
Pubmed
,
Xenbase
Bluemink,
Freeze-fracture electron microscopy of membrane changes in progesterone-induced maturing oocytes and eggs of Xenopus laevis.
1983,
Pubmed
,
Xenbase
Busa,
An elevated free cytosolic Ca2+ wave follows fertilization in eggs of the frog, Xenopus laevis.
1985,
Pubmed
,
Xenbase
Campanella,
The modifications of cortical endoplasmic reticulum during in vitro maturation of Xenopus laevis oocytes and its involvement in cortical granule exocytosis.
1984,
Pubmed
,
Xenbase
Capco,
Analysis of proteins in the peripheral and central regions of amphibian oocytes and eggs.
1988,
Pubmed
,
Xenbase
Capco,
Transient localizations of messenger RNA in Xenopus laevis oocytes.
1982,
Pubmed
,
Xenbase
Charbonneau,
The onset of activation responsiveness during maturation coincides with the formation of the cortical endoplasmic reticulum in oocytes of Xenopus laevis.
1984,
Pubmed
,
Xenbase
Elinson,
A transient array of parallel microtubules in frog eggs: potential tracks for a cytoplasmic rotation that specifies the dorso-ventral axis.
1988,
Pubmed
,
Xenbase
Franke,
Distribution and mode of arrangement of microfilamentous structures and actin in the cortex of the amphibian oocyte.
1976,
Pubmed
Gardiner,
Membrane junctions in Xenopus eggs: their distribution suggests a role in calcium regulation.
1983,
Pubmed
,
Xenbase
Godsave,
Intermediate filaments in the Xenopus oocyte: the appearance and distribution of cytokeratin-containing filaments.
1984,
Pubmed
,
Xenbase
Goldstein,
Receptor-mediated endocytosis: concepts emerging from the LDL receptor system.
1985,
Pubmed
Grey,
Formation and structure of the fertilization envelope in Xenopus laevis.
1974,
Pubmed
,
Xenbase
Kline,
Calcium-dependent events at fertilization of the frog egg: injection of a calcium buffer blocks ion channel opening, exocytosis, and formation of pronuclei.
1988,
Pubmed
,
Xenbase
Klymkowsky,
Polar asymmetry in the organization of the cortical cytokeratin system of Xenopus laevis oocytes and embryos.
1987,
Pubmed
,
Xenbase
Kubota,
Free calcium wave upon activation in Xenopus eggs.
1987,
Pubmed
,
Xenbase
Larabell,
Freeze-fracture analysis of structural reorganization during meiotic maturation in oocytes of Xenopus laevis.
1988,
Pubmed
,
Xenbase
Larabell,
Role of calcium in the localization of maternal poly(A)+RNA and tubulin mRNA in Xenopus oocytes.
1988,
Pubmed
,
Xenbase
Masui,
Oocyte maturation.
1979,
Pubmed
Morrill,
Endocytosis in the amphibian oocyte. Effect of insulin and progesterone on membrane and fluid internalization during the meiotic divisions.
1984,
Pubmed
Perry,
Spatial reorganization of actin, tubulin and histone mRNAs during meiotic maturation and fertilization in Xenopus oocytes.
1988,
Pubmed
,
Xenbase
Schuetz,
Steroid inhibition of protein incorporation by isolated amphibian oocytes.
1974,
Pubmed
,
Xenbase
Smith,
The induction of oocyte maturation: transmembrane signaling events and regulation of the cell cycle.
1989,
Pubmed
Wallace,
Protein incorporation by isolated amphibian oocytes. 3. Optimum incubation conditions.
1973,
Pubmed
,
Xenbase
Wallace,
Ultrastructural aspects of oogenesis and oocyte growth in fish and amphibians.
1990,
Pubmed
Weeks,
A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta.
1987,
Pubmed
,
Xenbase
