Houtmeyers R , Souopgui J , Tejpar S , Arkell R .

Ali, Zinc fingers of the cerebellum (Zic): transcription factors and co-factors. 2012, Pubmed

Ali, Zinc fingers of the cerebellum (Zic): transcription factors and co-factors. 2012, Pubmed
Arkell, Initiating head development in mouse embryos: integrating signalling and transcriptional activity. 2012, Pubmed
Aruga, The role of Zic genes in neural development. 2004, Pubmed
Aruga, Mouse Zic1 is involved in cerebellar development. 1998, Pubmed
Aruga, Zic1 regulates the patterning of vertebral arches in cooperation with Gli3. 1999, Pubmed , Xenbase
Aruga, Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation. 2002, Pubmed
Aruga, The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired. 1996, Pubmed
Aruga, A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells. 1994, Pubmed
Aruga, A wide-range phylogenetic analysis of Zic proteins: implications for correlations between protein structure conservation and body plan complexity. 2006, Pubmed
Aruga, Role of BMP, FGF, calcium signaling, and Zic proteins in vertebrate neuroectodermal differentiation. 2011, Pubmed , Xenbase
Bedard, Identification of a novel ZIC3 isoform and mutation screening in patients with heterotaxy and congenital heart disease. 2011, Pubmed
Blank, Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis. 2011, Pubmed
Brewster, Gli/Zic factors pattern the neural plate by defining domains of cell differentiation. 1998, Pubmed , Xenbase
Brown, Holoprosencephaly due to mutations in ZIC2: alanine tract expansion mutations may be caused by parental somatic recombination. 2001, Pubmed
Brown, In vitro analysis of partial loss-of-function ZIC2 mutations in holoprosencephaly: alanine tract expansion modulates DNA binding and transactivation. 2005, Pubmed
Brown, Zic2 is expressed in pluripotent cells in the blastocyst and adult brain expression overlaps with makers of neurogenesis. 2009, Pubmed , Xenbase
Carrel, The X-linked mouse mutation Bent tail is associated with a deletion of the Zic3 locus. 2000, Pubmed
Cast, An essential and highly conserved role for Zic3 in left-right patterning, gastrulation and convergent extension morphogenesis. 2012, Pubmed , Xenbase
Chan, A morphological and experimental study of the mesencephalic neural crest cells in the mouse embryo using wheat germ agglutinin-gold conjugate as the cell marker. 1988, Pubmed
Cheng, Central roles of the roof plate in telencephalic development and holoprosencephaly. 2006, Pubmed
Chhin, Elucidation of penetrance variability of a ZIC3 mutation in a family with complex heart defects and functional analysis of ZIC3 mutations in the first zinc finger domain. 2007, Pubmed , Xenbase
Chung, From VACTERL-H to heterotaxy: variable expressivity of ZIC3-related disorders. 2011, Pubmed
Coletta, Low-complexity regions within protein sequences have position-dependent roles. 2010, Pubmed
Dubourg, Holoprosencephaly. 2007, Pubmed
Elms, Zic2 is required for neural crest formation and hindbrain patterning during mouse development. 2003, Pubmed
Elms, Overlapping and distinct expression domains of Zic2 and Zic3 during mouse gastrulation. 2004, Pubmed
Fernandes, Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly. 2007, Pubmed
Franke, Phenotype of the neural tube defect mouse model bent tail is not sensitive to maternal folinic acid, myo-inositol, or zinc supplementation. 2003, Pubmed
Fujimi, Xenopus Zic3 controls notochord and organizer development through suppression of the Wnt/β-catenin signaling pathway. 2012, Pubmed , Xenbase
Fujimi, Xenopus Zic4: conservation and diversification of expression profiles and protein function among the Xenopus Zic family. 2006, Pubmed , Xenbase
Furushima, A new murine zinc finger gene, Opr. 2000, Pubmed
Furushima, Characterization of Opr deficiency in mouse brain: subtle defects in dorsomedial telencephalon and medioventral forebrain. 2005, Pubmed
Garber, "Bent-Tail," A Dominant, Sex-Linked Mutation in the Mouse. 1952, Pubmed
García-Frigola, Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms. 2008, Pubmed
Gaston-Massuet, Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system. 2005, Pubmed
Grinberg, Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation. 2004, Pubmed
Grinberg, The ZIC gene family in development and disease. 2005, Pubmed
GRUNEBERG, Heterosis and variability in the mouse. 1955, Pubmed
Gutkovich, Xenopus Meis3 protein lies at a nexus downstream to Zic1 and Pax3 proteins, regulating multiple cell-fates during early nervous system development. 2010, Pubmed , Xenbase
Hatayama, Characterization of the tandem CWCH2 sequence motif: a hallmark of inter-zinc finger interactions. 2010, Pubmed
Hatayama, Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain. 2008, Pubmed
Herrera, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. 2003, Pubmed
Houston, Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning. 2005, Pubmed , Xenbase
Inoue, Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives. 2004, Pubmed , Xenbase
Inoue, Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo. 2007, Pubmed
Inoue, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. 2008, Pubmed
Ishiguro, Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family. 2004, Pubmed
Johnson, The interfrontal bone and mutant genes in the mouse. 1976, Pubmed
Keller, Insights into the evolutionary history of the vertebrate zic3 locus from a teleost-specific zic6 gene in the zebrafish, Danio rerio. 2007, Pubmed
Klootwijk, Further characterization of the genetic defect of the Bent tail mouse, a mouse model for human neural tube defects. 2004, Pubmed
Klootwijk, A deletion encompassing Zic3 in bent tail, a mouse model for X-linked neural tube defects. 2000, Pubmed
Koyabu, Physical and functional interactions between Zic and Gli proteins. 2001, Pubmed
Kuo, Opl: a zinc finger protein that regulates neural determination and patterning in Xenopus. 1998, Pubmed , Xenbase
Layden, Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans. 2010, Pubmed
Leclerc, Calcium transients triggered by planar signals induce the expression of ZIC3 gene during neural induction in Xenopus. 2003, Pubmed , Xenbase
Leclerc, Imaging patterns of calcium transients during neural induction in Xenopus laevis embryos. 2000, Pubmed , Xenbase
Lee, Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1. 2008, Pubmed
Lim, The pluripotency regulator Zic3 is a direct activator of the Nanog promoter in ESCs. 2010, Pubmed
Marchal, BMP inhibition initiates neural induction via FGF signaling and Zic genes. 2009, Pubmed , Xenbase
Merzdorf, Emerging roles for zic genes in early development. 2007, Pubmed , Xenbase
Mizugishi, Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins. 2001, Pubmed , Xenbase
Mizugishi, Myogenic repressor I-mfa interferes with the function of Zic family proteins. 2004, Pubmed
Mizuseki, SoxD: an essential mediator of induction of anterior neural tissues in Xenopus embryos. 1998, Pubmed , Xenbase
Mizuseki, Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction. 1998, Pubmed , Xenbase
Monsoro-Burq, Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction. 2005, Pubmed , Xenbase
Moreau, Calcium signalling during neural induction in Xenopus laevis embryos. 2008, Pubmed , Xenbase
Nagai, Zic2 regulates the kinetics of neurulation. 2000, Pubmed
Nagai, The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation. 1997, Pubmed
Nakata, A novel member of the Xenopus Zic family, Zic5, mediates neural crest development. 2000, Pubmed , Xenbase
Nakata, Xenopus Zic family and its role in neural and neural crest development. 1998, Pubmed , Xenbase
Nakata, Xenopus Zic3, a primary regulator both in neural and neural crest development. 1997, Pubmed , Xenbase
Nyholm, The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum. 2007, Pubmed
Ogura, Behavioral abnormalities of Zic1 and Zic2 mutant mice: implications as models for human neurological disorders. 2001, Pubmed
Pan, A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis. 2011, Pubmed
Pérez-Pérez, Understanding synergy in genetic interactions. 2009, Pubmed
Pourebrahim, Transcription factor Zic2 inhibits Wnt/β-catenin protein signaling. 2011, Pubmed , Xenbase
Purandare, A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice. 2002, Pubmed
Quinn, Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice. 2012, Pubmed
Richardson, EMAGE mouse embryo spatial gene expression database: 2010 update. 2010, Pubmed
Robasky, UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein-DNA interactions. 2011, Pubmed
Roessler, The full spectrum of holoprosencephaly-associated mutations within the ZIC2 gene in humans predicts loss-of-function as the predominant disease mechanism. 2009, Pubmed
Rohr, Zebrafish zic1 expression in brain and somites is affected by BMP and hedgehog signalling. 1999, Pubmed
Salero, Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter. 2001, Pubmed
Satou, macho-1-Related genes in Ciona embryos. 2002, Pubmed
Sela-Donenfeld, Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube. 1999, Pubmed
Toyama, Sequence relationships and expression patterns of zebrafish zic2 and zic5 genes. 2004, Pubmed
Ware, Zic3 is critical for early embryonic patterning during gastrulation. 2006, Pubmed
Ware, Heart defects in X-linked heterotaxy: evidence for a genetic interaction of Zic3 with the nodal signaling pathway. 2006, Pubmed , Xenbase
Warr, Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation. 2008, Pubmed
Watabe, The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells. 2011, Pubmed
Wessels, Polyalanine expansion in the ZIC3 gene leading to X-linked heterotaxy with VACTERL association: a new polyalanine disorder? 2010, Pubmed
Ybot-Gonzalez, Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling. 2007, Pubmed
Zhang, Disruption of gradient expression of Zic3 resulted in abnormal intra-retinal axon projection. 2004, Pubmed
Zhu, Identification of a novel role of ZIC3 in regulating cardiac development. 2007, Pubmed
Zhu, Characterization of the interactions of human ZIC3 mutants with GLI3. 2008, Pubmed