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Emerg Infect Dis
2004 Dec 01;1012:2100-5. doi: 10.3201/eid1012.030804.
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Origin of the amphibian chytrid fungus.
Weldon C
,
du Preez LH
,
Hyatt AD
,
Muller R
,
Spears R
.
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The sudden appearance of chytridiomycosis, the cause of amphibian deaths and population declines in several continents, suggests that its etiologic agent, the amphibian chytrid Batrachochytrium dendrobatidis, was introduced into the affected regions. However, the origin of this virulent pathogen is unknown. A survey was conducted of 697 archived specimens of 3 species of Xenopus collected from 1879 to 1999 in southern Africa in which the histologic features of the interdigital webbing were analyzed. The earliest case of chytridiomycosis found was in a Xenopus laevis frog in 1938, and overall prevalence was 2.7%. The prevalence showed no significant differences between species, regions, season, or time period. Chytridiomycosis was a stable endemic infection in southern Africa for 23 years before any positive specimen was found outside Africa. We propose that Africa is the origin of the amphibian chytrid and that the international trade in X. laevis that began in the mid-1930s was the means of dissemination.
Figure 2. Historical time-trend of chytridiomycosis prevalence in southern Africa. No significant change was shown in the prevalence over time (p = 0.22, 95% confidence interval).
Figure 3. Time bar indicating when chytridiomycosis first appeared in the major centers of occurrence in relation to each other. Following a 23-year interruption in occurrences after the Xenopus laevis infection in 1938, records outside Africa appear with increasing frequency up until the present; North America (22), Australia (2,23), South America (5), Central America (24), Europe (6), Oceania (New Zealand) (25).
Berger,
Production of polyclonal antibodies to Batrachochytrium dendrobatidis and their use in an immunoperoxidase test for chytridiomycosis in amphibians.
2002, Pubmed
Berger,
Production of polyclonal antibodies to Batrachochytrium dendrobatidis and their use in an immunoperoxidase test for chytridiomycosis in amphibians.
2002,
Pubmed
Berger,
Chytridiomycosis causes amphibian mortality associated with population declines in the rain forests of Australia and Central America.
1998,
Pubmed
Carey,
Amphibian declines: an immunological perspective.
1999,
Pubmed
,
Xenbase
Daszak,
Emerging infectious diseases and amphibian population declines.
1999,
Pubmed
Johnson,
Survival of Batrachochytrium dendrobatidis in water: quarantine and disease control implications.
2003,
Pubmed
Lane,
Histological evidence of chytridiomycete fungal infection in a free-ranging amphibian, Afrana fuscigula (Anura: Ranidae), in South Africa.
2003,
Pubmed
Mazzoni,
Emerging pathogen of wild amphibians in frogs (Rana catesbeiana) farmed for international trade.
2003,
Pubmed
Morehouse,
Multilocus sequence typing suggests the chytrid pathogen of amphibians is a recently emerged clone.
2003,
Pubmed
Morse,
Factors in the emergence of infectious diseases.
1995,
Pubmed
Mutschmann,
[Chytridiomycosis in amphibians--first report in Europe].
2000,
Pubmed
Parker,
Clinical diagnosis and treatment of epidermal chytridiomycosis in African clawed frogs (Xenopus tropicalis).
2002,
Pubmed
,
Xenbase
Reed,
Chlamydia pneumoniae infection in a breeding colony of African clawed frogs (Xenopus tropicalis).
2000,
Pubmed
,
Xenbase
Rollins-Smith,
Antimicrobial peptide defenses of the Tarahumara frog, Rana tarahumarae.
2002,
Pubmed
