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Anat Embryol (Berl)
1982 Jan 01;1634:461-73. doi: 10.1007/bf00305559.
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Observations on the development of descending pathways from the brain stem to the spinal cord in the clawed toad Xenopus laevis.
ten Donkelaar HJ
,
de Boer-van Huizen R
.
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Anurans such as the clawed toad Xenopus laevis offer a unique opportunity to study the ontogeny of descending pathways to the spinal cord. Their transition from aquatic limbless tadpole to juvenile toad occurs over a protracted period time during which the animal is accessible for experimental studies. In Xenopus laevis tadpoles the development of descending pathways has been studied from early limb-bud stage on (stage 50) with the aid of HRP slow-release gels. In stage 50, cells of origin of descending supraspinal pathways were already present throughout the reticular formation (including the interstitial nucleus of the fasciculus longitudinalis medialis) and in the vestibular nuclear complex. Also the giant Mauthner cells project to the cord at this stage. A spinal projection from the anuran homologue of the nucleus ruber of higher vertebrates does not appear before stage 58, i.e., when the hindlimbs are used for locomotion. Hypothalamospinal projections appear for the first time at stage 57. These observations in Xenopus laevis tadpoles suggest that reticulospinal and vestibulospinal projections innervate spinal segments very early in development, whereas the anuran red nucleus projects spinal ward definitely later in development.
Billings,
Development of the Mauthner cell in Xenopus laevis: a light and electron microscopic study of the Perikaryon.
1972, Pubmed,
Xenbase
Billings,
Development of the Mauthner cell in Xenopus laevis: a light and electron microscopic study of the Perikaryon.
1972,
Pubmed
,
Xenbase
Cabana,
The origin of brain stem-spinal projections at different stages of development in the North American opossum.
1981,
Pubmed
Graham,
Glomerular permeability. Ultrastructural cytochemical studies using peroxidases as protein tracers.
1966,
Pubmed
Grant,
Ontogeny of the retina and optic nerve in Xenopus laevis. II. Ontogeny of the optic fiber pattern in the retina.
1980,
Pubmed
,
Xenbase
Griffin,
HRP pellets and slow-release gels: two new techniques for greater localization and sensitivity.
1979,
Pubmed
Humbertson,
The development of monoaminergic brainstem-spinal systems in the North American opossum.
1979,
Pubmed
Katz,
Ontogeny of substrate pathways and the origin of the neural circuit pattern.
1980,
Pubmed
,
Xenbase
Katz,
Substrate pathways which guide growing axons in Xenopus embryos.
1979,
Pubmed
,
Xenbase
Katz,
Substrate pathways demonstrated by transplanted Mauthner axons.
1981,
Pubmed
,
Xenbase
Martin,
The early development of corticobulbar and corticospinal systems. Studies using the North American opossum.
1980,
Pubmed
Martin,
Observations on the development of brainstem-spinal systems in the North American oppossum.
1978,
Pubmed
Mesulam,
Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents.
1978,
Pubmed
Moulton,
A cytological study of Mauthner's cells in Xenopus laevis and Rana temporaria during metamorphosis.
1968,
Pubmed
,
Xenbase
Rovainen,
Neurobiology of lampreys.
1979,
Pubmed
Singer,
Axonal guidance during embryogenesis and regeneration in the spinal cord of the newt: the blueprint hypothesis of neuronal pathway patterning.
1979,
Pubmed
STEFANELLI,
The mauthnerian apparatus in the Ichthyopsida; its nature and function and correlated problems of neurohistogenesis.
1951,
Pubmed
TAYLOR,
Stages in the normal development of Rana pipiens larvae.
1946,
Pubmed
ten Donkelaar,
Cells of origin of descending pathways to the spinal cord in the clawed toad (Xenopus laevis).
1981,
Pubmed
,
Xenbase
Ten Donkelaar,
Descending pathways from the brain stem to the spinal cord in some reptiles. II. Course and site of termination.
1976,
Pubmed
Tohyama,
Comparative anatomy of the locus coeruleus. II. Organization and projection of the catecholamine containing neurons in the upper rhombencephalon of the frog, Rana catesbiana.
1976,
Pubmed
Yamamoto,
Comparative anatomy of the topography of catecholamine containing neuron system in the brain stem from birds to teleosts.
1977,
Pubmed
