XB-ART-26817
Biochem Biophys Res Commun
1989 Apr 28;1602:615-22.
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Evidence for a novel growth factor in Xenopus oocytes.
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Xenopus oocytes contain a novel growth factor, as determined by its effect on the anchorage-dependent and -independent growth of various rat cells and on a Xenopus cell line; it is destroyed by trypsin, acidification (pH 2.0), heating (100 degrees C, 3 min), 8 M urea but not by dithiothreitol. Gel filtration of this activity in nondissociating conditions suggests the existence of aggregates and the presence of a very high (approximately 2000 Kd) and a much lower (approximately 30 Kd) form.
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Species referenced: Xenopus
Genes referenced: prss1