XB-ART-24030
Curr Opin Immunol
1992 Feb 01;41:3-7.
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Antibiotic peptides as mediators of innate immunity.
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Antibiotic peptides are widely distributed in nature. Almost all function as membrane-active agents, disrupting target-cell permeability. Several exhibit a striking selectivity for single-celled microbes over metazoan cells, and as such are amongst the simplest components of the animal's defensive system, which distinguishes environmental microbes from 'self'.
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