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Exp Brain Res
1989 Jan 01;751:99-116. doi: 10.1007/bf00248534.
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Changing patterns of binocular visual connections in the intertectal system during development of the frog, Xenopus laevis. I. Normal maturational changes in response to changing binocular geometry.
Grant S
,
Keating MJ
.
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During metamorphic and post-metamorphic life in the frog. Xenopus laevis, growth-related changes in skull shape produce radical alterations in the spatial relationship between the two eyes. These changes in binocular visual geometry were measured using optical techniques. Between the onset of metamorphic climax at stage 60 and adulthood (2 or more years post-metamorphosis) each eye migrates nasally by 55 degrees and dorsally by 50 degrees with respect to the major body axes of the animal. As a result the nasotemporal extent of the binocular visual field increases from 30 degrees to 162 degrees between these ages. Electrophysiological methods were used to determine changes in the neural representation of the binocular visual field at the paired midbrain optic tecta and in the tectal projection of pairs of corresponding retinal loci at various developmental points between these ages. The proportion of each tectal surface devoted to the representation of the binocular visual field increases from 11% at stage 60 to 77% at adulthood. Retinal correspondence, and hence the tectal projection of corresponding retinal loci, undergoes radical alteration during this period. In normal adults an intertectal system of connections selectively links the tectal projection of corresponding retinal loci and thus provides a neuronal mechanism for integrating binocular visual information in the optic tecta. Electrophysiological methods were used to determine how the intertectal system accommodates the developmental challenge posed by the enlarging binocular visual field and changing retinal correspondence. Between stage 60 and adulthood the ipsilateral visuotectal projection which is the product of the intertectal system, increases in size as the binocular visual field and its tectal representation enlarges. Moreover, throughout this period, it provides a mechanism for integrating binocular visual information in the optic tecta by maintaining its spatial registration with the contralateral visuotectal projection from the other eye. Analysis of the pattern of functional intertectal connections reveals that during the course of normal maturation this system undergoes continuous processes of expansion and of orderly and major remodelling.
Beazley,
The appearance, during development, of responses in the optic tectum following visual stimulation of the ipsilateral eye in Xenopus laevis.
1972, Pubmed,
Xenbase
Beazley,
The appearance, during development, of responses in the optic tectum following visual stimulation of the ipsilateral eye in Xenopus laevis.
1972,
Pubmed
,
Xenbase
Bishop,
Stereopsis and the random element in the organization of the striate cortex.
1979,
Pubmed
Collett,
Stereopsis in toads.
1977,
Pubmed
Cook,
A pattern of optic axons in the normal goldfish tectum consistent with the caudal migration of optic terminals during development.
1983,
Pubmed
Dunlop,
A morphometric study of the retinal ganglion cell layer and optic nerve from metamorphosis in Xenopus laevis.
1984,
Pubmed
,
Xenbase
Easter,
An evaluation of the hypothesis of shifting terminals in goldfish optic tectum.
1984,
Pubmed
Fite,
The visual fields of the frog and toad: a comparative study.
1973,
Pubmed
Fraser,
Fiber optic mapping of the Xenopus visual system: shift in the retinotectal projection during development.
1983,
Pubmed
,
Xenbase
Fujisawa,
Mode of growth of retinal axons within the tectum of Xenopus tadpoles, and implications in the ordered neuronal connection between the retina and the tectum.
1987,
Pubmed
,
Xenbase
Gaillard,
Mapping studies of the tectal representation of the frog binocular visual field. A problem of methodology.
1981,
Pubmed
Gaze,
The evolution of the retinotectal map during development in Xenopus.
1974,
Pubmed
,
Xenbase
Gaze,
Binocular interaction in the formation of specific intertectal neuronal connexions.
1970,
Pubmed
Gaze,
The relationship between retinal and tectal growth in larval Xenopus: implications for the development of the retino-tectal projection.
1979,
Pubmed
,
Xenbase
Glasser,
The nucleus isthmus as a relay station in the ipsilateral visual projection to the frog's optic tectum.
1978,
Pubmed
Grant,
Ocular migration and the metamorphic and postmetamorphic maturation of the retinotectal system in Xenopus laevis: an autoradiographic and morphometric study.
1986,
Pubmed
,
Xenbase
Grant,
Normal maturation involves systematic changes in binocular visual connections in Xenopus laevis.
,
Pubmed
,
Xenbase
Grant,
Changing patterns of binocular visual connections in the intertectal system during development of the frog, Xenopus laevis. II. Abnormalities following early visual deprivation.
1989,
Pubmed
,
Xenbase
Grobstein,
Post-metamorphic eye migration in Rana and Xenopus.
1977,
Pubmed
,
Xenbase
Grobstein,
A crossed isthmo-tectal projection in Rana pipiens and its involvement in the ipsilateral visuotectal projection.
1978,
Pubmed
Grobstein,
The potential binocular field and its tectal representation in Rana pipiens.
1980,
Pubmed
Hitchcock,
Evidence for centripetally shifting terminals on the tectum of postmetamorphic Rana pipiens.
1987,
Pubmed
Keating,
Evidence for plasticity of intertectal neuronal connections in adult Xenopus.
1977,
Pubmed
,
Xenbase
Keating,
The role of visual function in the patterning of binocular visual connexions.
1974,
Pubmed
,
Xenbase
Keating,
Visual experience and the maturation of the ipsilateral visuotectal projection in Xenopus laevis.
1987,
Pubmed
,
Xenbase
Keating,
Functional interaction in the development of specific nerve connections.
1968,
Pubmed
Keating,
The ipsilateral retinotectal pathway in the frog.
1970,
Pubmed
Keating,
Visual deprivation and intertectal neuronal connexions in Xenopus laevis.
1975,
Pubmed
,
Xenbase
Meyer,
Evidence from thymidine labeling for continuing growth of retina and tectum in juvenile goldfish.
1978,
Pubmed
Niu,
The Differentiation of Gastrula Ectoderm in Medium Conditioned by Axial Mesoderm.
1953,
Pubmed
Raybourn,
Spatial and temporal organization of the binocular input to frog optic tectum.
1975,
Pubmed
Raymond,
Postembryonic growth of the optic tectum in goldfish. I. Location of germinal cells and numbers of neurons produced.
1983,
Pubmed
Reh,
Retinal ganglion cell terminals change their projection sites during larval development of Rana pipiens.
1984,
Pubmed
Reh,
Qualitative and quantitative measures of plasticity during the normal development of the Rana pipiens retinotectal projection.
1983,
Pubmed
Scott,
An investigation into the hypothesis of shifting neuronal relationships during development.
1976,
Pubmed
,
Xenbase
Udin,
The development of the nucleus isthmi in Xenopus laevis. I. Cell genesis and the formation of connections with the tectum.
1985,
Pubmed
,
Xenbase
Udin,
Plasticity in a central nervous pathway in xenopus: anatomical changes in the isthmotectal projection after larval eye rotation.
1981,
Pubmed
,
Xenbase
Udin,
The role of visual experience in the formation of binocular projections in frogs.
1985,
Pubmed
,
Xenbase
Udin,
Abnormal visual input leads to development of abnormal axon trajectories in frogs.
1983,
Pubmed
,
Xenbase
