Semin Cell Dev Biol 2006 Feb 01;171:80-92. doi: 10.1016/j.semcdb.2005.11.001.

There's more than one frog in the pond: a survey of the Amphibia and their contributions to developmental biology.

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The study of developmental biology has benefited greatly from the insights gained using amphibians as experimental models. Although Xenopus is currently the predominant model, much of our embryological knowledge derives from research on other amphibians. I will review some of these discoveries, made through astute choice of model organism, and I will examine the reasons behind the adoption of Xenopus as the standard for amphibian research. Additionally, I will discuss the diversity in developmental and reproductive strategies that exists within the Amphibia, and consider some of the recent advances in our understanding of the mechanisms underlying this developmental diversity.

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