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Inhibition of Na-alanine cotransport in oocytes of Xenopus laevis during meiotic maturation is voltage-regulated.
Jung D
,
Lafaire AV
,
Schwarz W
.
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During progesterone-induced maturation of oocytes of Xenopus laevis the fast decrease of the rate of Na+-alanine cotransport is accompanied by a depolarization of the membrane potential and an increase in the intracellular Na+ activity. It is demonstrated that the decrease of the Na+-dependent alanine uptake is the result of the depolarization while the simultaneous increase in intracellular Na+ activity has no significant effect.
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