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Xenopus laevis 5S rRNA isolated from 7S particles or transcribed in vitro is found to adopt two alternative conformations. These two conformers contain different structural elements within the major TF III A binding domain, which, when isolated as RNA fragments, still interact with the transcription factor. Chemical modification of easily accessible adenines in their N-1 position does not have any measurable effect on the binding of 5S rRNA to TF III A. These observations are in support of the idea that only a small amount of conserved sequence information is required for the binding of the transcription factor, whereas specific secondary structure features seem to be essential.
Andersen,
Characterization of RNA-protein interactions in 7 S ribonucleoprotein particles from Xenopus laevis oocytes.
1986, Pubmed,
Xenbase
Andersen,
Characterization of RNA-protein interactions in 7 S ribonucleoprotein particles from Xenopus laevis oocytes.
1986,
Pubmed
,
Xenbase
Andersen,
5S RNA structure and interaction with transcription factor A. 2. Ribonuclease probe of the 7S particle from Xenopus laevis immature oocytes and RNA exchange properties of the 7S particle.
1984,
Pubmed
,
Xenbase
Andersen,
5S RNA structure and interaction with transcription factor A. 1. Ribonuclease probe of the structure of 5S RNA from Xenopus laevis oocytes.
1984,
Pubmed
,
Xenbase
Bogenhagen,
Nucleotide sequences in Xenopus 5S DNA required for transcription termination.
1981,
Pubmed
,
Xenbase
Brown,
The primary structure of transcription factor TFIIIA has 12 consecutive repeats.
1985,
Pubmed
,
Xenbase
Digweed,
Improved procedure for the isolation of a double-strand-specific ribonuclease and its application to structural analysis of various 5S rRNAs and tRNAs.
1986,
Pubmed
Donis-Keller,
Mapping adenines, guanines, and pyrimidines in RNA.
1977,
Pubmed
Engelke,
Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes.
1980,
Pubmed
,
Xenbase
Erdmann,
Collection of published 5S, 5.8S and 4.5S ribosomal RNA sequences.
1985,
Pubmed
Folk,
A detailed mutational analysis of the eucaryotic tRNAmet1 gene promoter.
1983,
Pubmed
,
Xenbase
Ginsberg,
Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development.
1984,
Pubmed
,
Xenbase
Hanas,
DNA unwinding ability of Xenopus transcription factor A.
1984,
Pubmed
,
Xenbase
Hanas,
Binding of Xenopus transcription factor A to 5S RNA and to single stranded DNA.
1984,
Pubmed
,
Xenbase
Huber,
Use of the cytotoxic nuclease alpha-sarcin to identify the binding site on eukaryotic 5 S ribosomal ribonucleic acid for the ribosomal protein L5.
1986,
Pubmed
,
Xenbase
Miller,
Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.
1985,
Pubmed
,
Xenbase
Peattie,
A "bulged" double helix in a RNA-protein contact site.
1981,
Pubmed
Peattie,
Chemical probes for higher-order structure in RNA.
1980,
Pubmed
Picard,
Isolation of a 7S particle from Xenopus laevis oocytes: a 5S RNA-protein complex.
1979,
Pubmed
,
Xenbase
Pieler,
Functional domains of the Xenopus laevis 5S gene promoter.
1985,
Pubmed
,
Xenbase
Pieler,
Isolation and characterization of a 7 S RNP particle from mature Xenopus laevis oocytes.
1983,
Pubmed
,
Xenbase
Pieler,
Comparative structural analysis of eubacterial 5S rRNA by oxidation of adenines in the N-1 position.
1984,
Pubmed
Pieler,
Point mutational analysis of the Xenopus laevis 5S gene promoter.
1985,
Pubmed
,
Xenbase
Pieler,
Structural requirements for the interaction of 5S rRNA with the eukaryotic transcription factor IIIA.
1984,
Pubmed
,
Xenbase
Reynolds,
5S rRNA gene transcription factor IIIA alters the helical configuration of DNA.
1983,
Pubmed
,
Xenbase
Romaniuk,
Characterization of the RNA binding properties of transcription factor IIIA of Xenopus laevis oocytes.
1985,
Pubmed
,
Xenbase
Sakonju,
Contact points between a positive transcription factor and the Xenopus 5S RNA gene.
1982,
Pubmed
,
Xenbase
Sakonju,
The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene.
1981,
Pubmed
,
Xenbase
Smith,
Domains of the positive transcription factor specific for the Xenopus 5S RNA gene.
1984,
Pubmed
,
Xenbase
Tinoco,
Estimation of secondary structure in ribonucleic acids.
1971,
Pubmed
Volckaert,
Micro thin-layer techniques for rapid sequence analysis of 32P-labeled RNA: double digestion and pancreatic ribonuclease analyses.
1977,
Pubmed
Wakefield,
Cytoplasmic regulation of 5S RNA genes in nuclear-transplant embryos.
1983,
Pubmed
,
Xenbase
Wegnez,
Sequence heterogeneity of 5 S RNA in Xenopus laevis.
1972,
Pubmed
,
Xenbase
