Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Mol Cell
2003 Dec 01;126:1599-606. doi: 10.1016/s1097-2765(03)00499-4.
Show Gene links
Show Anatomy links
Histone H2A/H2B dimer exchange by ATP-dependent chromatin remodeling activities.
Bruno M
,
Flaus A
,
Stockdale C
,
Rencurel C
,
Ferreira H
,
Owen-Hughes T
.
???displayArticle.abstract???
ATP-dependent chromatin remodeling activities function to manipulate chromatin structure during gene regulation. One of the ways in which they do this is by altering the positions of nucleosomes along DNA. Here we provide support for the ability of these complexes to move nucleosomes into positions in which DNA is unraveled from one edge. This is expected to result in the loss of histone-DNA contacts that are important for retention of one H2A/H2B dimer within the nucleosome. Consistent with this we find that several chromatin remodeling complexes are capable of catalyzing the exchange of H2A/H2B dimers between chromatin fragments in an ATP-dependent reaction. This provides eukaryotes with additional means by which they may manipulate chromatin structure.
Andrews,
The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions.
2010, Pubmed,
Xenbase
Andrews,
The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions.
2010,
Pubmed
,
Xenbase
Andrews,
A thermodynamic model for Nap1-histone interactions.
2008,
Pubmed
,
Xenbase
Annunziato,
Split decision: what happens to nucleosomes during DNA replication?
2005,
Pubmed
Baxevanis,
Associative behavior of the histone (H3-H4)2 tetramer: dependence on ionic environment.
1991,
Pubmed
Berndsen,
Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75.
2008,
Pubmed
,
Xenbase
Bowman,
Probing the (H3-H4)2 histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling.
2010,
Pubmed
,
Xenbase
Chang,
Histones in transit: cytosolic histone complexes and diacetylation of H4 during nucleosome assembly in human cells.
1997,
Pubmed
Chen,
Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair.
2008,
Pubmed
Daganzo,
Structure and function of the conserved core of histone deposition protein Asf1.
2003,
Pubmed
Das,
The histone shuffle: histone chaperones in an energetic dance.
2010,
Pubmed
Dutta,
The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly.
2001,
Pubmed
English,
Structural basis for the histone chaperone activity of Asf1.
2006,
Pubmed
,
Xenbase
English,
ASF1 binds to a heterodimer of histones H3 and H4: a two-step mechanism for the assembly of the H3-H4 heterotetramer on DNA.
2005,
Pubmed
Fillingham,
Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109.
2008,
Pubmed
Finn,
sNASP, a histone H1-specific eukaryotic chaperone dimer that facilitates chromatin assembly.
2008,
Pubmed
Gill,
Crystal structure of malaria parasite nucleosome assembly protein: distinct modes of protein localization and histone recognition.
2009,
Pubmed
Hansen,
Histone chaperones, histone acetylation, and the fluidity of the chromogenome.
2010,
Pubmed
Henikoff,
Nucleosome destabilization in the epigenetic regulation of gene expression.
2008,
Pubmed
Jackson,
In vivo studies on the dynamics of histone-DNA interaction: evidence for nucleosome dissolution during replication and transcription and a low level of dissolution independent of both.
1990,
Pubmed
Kaplan,
Cell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast.
2008,
Pubmed
Kobashi,
Catalytic oxidation of sulfhydryl groups by o-phenanthroline copper complex.
1968,
Pubmed
Krogan,
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
2006,
Pubmed
Laskey,
Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA.
1978,
Pubmed
,
Xenbase
Li,
Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly.
2008,
Pubmed
Longtine,
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae.
1998,
Pubmed
Lorch,
Chromatin remodeling by nucleosome disassembly in vitro.
2006,
Pubmed
Luger,
Characterization of nucleosome core particles containing histone proteins made in bacteria.
1997,
Pubmed
,
Xenbase
McBryant,
Preferential binding of the histone (H3-H4)2 tetramer by NAP1 is mediated by the amino-terminal histone tails.
2003,
Pubmed
,
Xenbase
Mosammaparast,
Nuclear import of histone H2A and H2B is mediated by a network of karyopherins.
2001,
Pubmed
Mousson,
Structural basis for the interaction of Asf1 with histone H3 and its functional implications.
2005,
Pubmed
Natsume,
Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4.
2007,
Pubmed
,
Xenbase
Park,
The structure of nucleosome assembly protein 1.
2006,
Pubmed
Park,
Histone chaperone specificity in Rtt109 activation.
2008,
Pubmed
Park,
Histone chaperones in nucleosome eviction and histone exchange.
2008,
Pubmed
Park,
A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1.
2008,
Pubmed
Park,
Structure and function of nucleosome assembly proteins.
2006,
Pubmed
Prior,
Incorporation of exogenous pyrene-labeled histone into Physarum chromatin: a system for studying changes in nucleosomes assembled in vivo.
1980,
Pubmed
Puig,
The tandem affinity purification (TAP) method: a general procedure of protein complex purification.
2001,
Pubmed
Richardson,
Characterization of the histone H1-binding protein, NASP, as a cell cycle-regulated somatic protein.
2000,
Pubmed
,
Xenbase
Richmond,
The structure of DNA in the nucleosome core.
2003,
Pubmed
Schermer,
Histones are incorporated in trans during reassembly of the yeast PHO5 promoter.
2005,
Pubmed
Selth,
Vps75, a new yeast member of the NAP histone chaperone family.
2007,
Pubmed
Tagami,
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis.
2004,
Pubmed
Tang,
Structure of Vps75 and implications for histone chaperone function.
2008,
Pubmed
Thåström,
Sequence motifs and free energies of selected natural and non-natural nucleosome positioning DNA sequences.
1999,
Pubmed
Tóth,
Association states of nucleosome assembly protein 1 and its complexes with histones.
2005,
Pubmed
Tsubota,
Histone H3-K56 acetylation is catalyzed by histone chaperone-dependent complexes.
2007,
Pubmed
Tyler,
The RCAF complex mediates chromatin assembly during DNA replication and repair.
1999,
Pubmed
Wang,
Expanded binding specificity of the human histone chaperone NASP.
2008,
Pubmed
Xu,
Partitioning of histone H3-H4 tetramers during DNA replication-dependent chromatin assembly.
2010,
Pubmed
Zhang,
Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase.
1998,
Pubmed
