Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-22712
Trends Biochem Sci 1993 Apr 01;184:128-31.
Show Gene links Show Anatomy links

The MAP kinase cascade is essential for diverse signal transduction pathways.

Nishida E , Gotoh Y .


???displayArticle.abstract???
Mitogen-activated protein (MAP) kinases are activated by combined tyrosine and threonine phosphorylation catalysed by MAP kinase kinase, a novel class of protein kinases with dual specificity for both tyrosine and serine/threonine. MAP kinase kinase is turned on by serine/threonine phosphorylation catalysed by an immediate upstream kinase. The MAP kinase cascade appears to be conserved during evolution and thus might play an essential role in diverse intracellular signaling processes from yeasts to vertebrates.

???displayArticle.pubmedLink??? 8388132
???displayArticle.link??? Trends Biochem Sci


Species referenced: Xenopus
Genes referenced: mapk1