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Nucleic Acids Res
2002 Jan 01;301:109-12. doi: 10.1093/nar/30.1.109.
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Wanda: a database of duplicated fish genes.
Van de Peer Y
,
Taylor JS
,
Joseph J
,
Meyer A
.
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Comparative genomics has shown that ray-finned fish (Actinopterygii) contain more copies of many genes than other vertebrates. A large number of these additional genes appear to have been produced during a genome duplication event that occurred early during the evolution of Actinopterygii (i.e. before the teleost radiation). In addition to this ancient genome duplication event, many lineages within Actinopterygii have experienced more recent genome duplications. Here we introduce a curated database named Wanda that lists groups of orthologous genes with one copy from man, mouse and chicken, one or two from tetraploid Xenopus and two or more ancient copies (i.e. paralogs) from ray-finned fish. The database also contains the sequence alignments and phylogenetic trees that were necessary for determining the correct orthologous and paralogous relationships among genes. Where available, map positions and functional data are also reported. The Wanda database should be of particular use to evolutionary and developmental biologists who are interested in the evolutionary and functional divergence of genes after duplication. Wanda is available at http://www.evolutionsbiologie.uni-konstanz.de/Wanda/.
Allendorf,
Gene duplication in the family Salmonidae. III. Linkage between two duplicated loci coding for aspartate aminotransferase in the cutthroat trout (Salmo clarki).
1976, Pubmed
Allendorf,
Gene duplication in the family Salmonidae. III. Linkage between two duplicated loci coding for aspartate aminotransferase in the cutthroat trout (Salmo clarki).
1976,
Pubmed
Altschul,
Basic local alignment search tool.
1990,
Pubmed
Amores,
Zebrafish hox clusters and vertebrate genome evolution.
1998,
Pubmed
Aparicio,
Vertebrate evolution: recent perspectives from fish.
2000,
Pubmed
Aparicio,
Organization of the Fugu rubripes Hox clusters: evidence for continuing evolution of vertebrate Hox complexes.
1997,
Pubmed
Bailey,
Gene duplication in tetraploid fish: model for gene silencing at unlinked duplicated loci.
1978,
Pubmed
Dingerkus,
Karyotypic analysis and evidence of tetraploidy in the North American paddlefish, Polyodon spathula.
1976,
Pubmed
Ekker,
Relationships among msx gene structure and function in zebrafish and other vertebrates.
1997,
Pubmed
Ferris,
Loss of duplicate gene expression after polyploidisation.
1977,
Pubmed
Fitch,
Homology a personal view on some of the problems.
2000,
Pubmed
Force,
Preservation of duplicate genes by complementary, degenerative mutations.
1999,
Pubmed
Gates,
A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences.
1999,
Pubmed
Gibson,
Genetic redundancy in vertebrates: polyploidy and persistence of genes encoding multidomain proteins.
1998,
Pubmed
Kappen,
Analysis of a complete homeobox gene repertoire: implications for the evolution of diversity.
2000,
Pubmed
Laforest,
Involvement of the sonic hedgehog, patched 1 and bmp2 genes in patterning of the zebrafish dermal fin rays.
1998,
Pubmed
Li,
Rate of gene silencing at duplicate loci: a theoretical study and interpretation of data from tetraploid fishes.
1980,
Pubmed
Lynch,
The evolutionary fate and consequences of duplicate genes.
2000,
Pubmed
Lynch,
The probability of duplicate gene preservation by subfunctionalization.
2000,
Pubmed
Martínez-Barberá,
Cloning and expression of three members of the zebrafish Bmp family: Bmp2a, Bmp2b and Bmp4.
1997,
Pubmed
,
Xenbase
Meyer,
Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions.
1999,
Pubmed
Naruse,
A detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolution.
2000,
Pubmed
Nowak,
Evolution of genetic redundancy.
1997,
Pubmed
Postlethwait,
Zebrafish comparative genomics and the origins of vertebrate chromosomes.
2000,
Pubmed
Robinson-Rechavi,
Euteleost fish genomes are characterized by expansion of gene families.
2001,
Pubmed
Robinson-Rechavi,
An ancestral whole-genome duplication may not have been responsible for the abundance of duplicated fish genes.
2001,
Pubmed
Sharman,
Some new terms for duplicated genes.
1999,
Pubmed
Sprague,
The Zebrafish Information Network (ZFIN): a resource for genetic, genomic and developmental research.
2001,
Pubmed
Stoesser,
The EMBL nucleotide sequence database.
2001,
Pubmed
Taylor,
Genome duplication, divergent resolution and speciation.
2001,
Pubmed
Taylor,
Comparative genomics provides evidence for an ancient genome duplication event in fish.
2001,
Pubmed
,
Xenbase
Thompson,
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.
1997,
Pubmed
Uyeno,
Tetraploid origin of the karyotype of catostomid fishes.
1972,
Pubmed
Van de Peer,
The ghost of selection past: rates of evolution and functional divergence of anciently duplicated genes.
2001,
Pubmed
,
Xenbase
Wheeler,
Database resources of the National Center for Biotechnology Information.
2001,
Pubmed
Woods,
A comparative map of the zebrafish genome.
2000,
Pubmed
