Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-40464
Trends Parasitol 2009 Jun 01;256:246-9. doi: 10.1016/j.pt.2009.03.006.
Show Gene links Show Anatomy links

Purine uptake in Plasmodium: transport versus metabolism.

Kirk K , Howitt SM , Bröer S , Saliba KJ , Downie MJ .


???displayArticle.abstract???
In a recent paper, Quashie et al. have proposed that purine uptake into the intraerythrocytic malaria parasite involves four different plasma membrane transporters - two high affinity and two low affinity. They equate one of the two high-affinity transporters with PfNT1, a transporter reported previously to be a low-affinity system. Here, we offer an alternative interpretation of their data, suggesting that the conclusions drawn by Quashie et al. take insufficient account of metabolism.

???displayArticle.pubmedLink??? 19423394
???displayArticle.link??? Trends Parasitol


Species referenced: Xenopus laevis
Genes referenced: tbx2