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XB-ART-34590
Mol Cell 2006 Apr 21;222:156-7. doi: 10.1016/j.molcel.2006.04.005.
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Climbing the Greatwall to mitosis.



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Greatwall kinase is a conserved regulator of mitotic entry, and new work in Xenopus egg extracts (Yu et al., 2006) shows that Greatwall is required for the positive feedback loop that removes inhibitory tyrosine phosphate from the central mitotic regulatory kinase Cdc2.

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Species referenced: Xenopus laevis
Genes referenced: cdk1 mastl tbx2

References :
Yu, Greatwall kinase participates in the Cdc2 autoregulatory loop in Xenopus egg extracts. 2006, Pubmed, Xenbase