XB-ART-52296
Dongwuxue Yanjiu
2016 Jul 18;374:237-45. doi: 10.13918/j.issn.2095-8137.2016.4.237.
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Research proceedings on amphibian model organisms.
Liu LS
,
Zhao LY
,
Wang SH
,
Jiang JP
.
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Model organisms have long been important in biology and medicine due to their specific characteristics. Amphibians, especially Xenopus, play key roles in answering fundamental questions on developmental biology, regeneration, genetics, and toxicology due to their large and abundant eggs, as well as their versatile embryos, which can be readily manipulated and developed in vivo. Furthermore, amphibians have also proven to be of considerable benefit in human disease research due to their conserved cellular developmental and genomic organization. This review gives a brief introduction on the progress and limitations of these animal models in biology and human disease research, and discusses the potential and challenge of Microhyla fissipes as a new model organism.
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