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Neuron
2009 Mar 26;616:895-905. doi: 10.1016/j.neuron.2009.01.018.
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Subcellular topography of visually driven dendritic activity in the vertebrate visual system.
Bollmann JH
,
Engert F
.
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Neural pathways projecting from sensory organs to higher brain centers form topographic maps in which neighbor relationships are preserved from a sending to a receiving neural population. Sensory input can generate compartmentalized electrical and biochemical activity in the dendrites of a receiving neuron. Here, we show that in the developing retinotectal projection of young Xenopus tadpoles, visually driven Ca2+ signals are topographically organized at the subcellular, dendritic scale. Functional in vivo two-photon Ca2+ imaging revealed that the sensitivity of dendritic Ca2+ signals to stimulus location in visual space is correlated with their anatomical position within the dendritic tree of individual neurons. This topographic distribution was dependent on NMDAR activation, whereas global Ca2+ signals were mediated by Ca2+ influx through dendritic, voltage-dependent Ca2+ channels. These findings suggest a framework for plasticity models that invoke local dendritic Ca2+ signaling in the elaboration of neural connectivity and dendrite-specific information storage.
Aizenman,
Visually driven regulation of intrinsic neuronal excitability improves stimulus detection in vivo.
2003, Pubmed,
Xenbase
Aizenman,
Visually driven regulation of intrinsic neuronal excitability improves stimulus detection in vivo.
2003,
Pubmed
,
Xenbase
Baden,
Neurite-specific Ca2+ dynamics underlying sound processing in an auditory interneurone.
2007,
Pubmed
Bollmann,
Postsynaptic Ca2+ influx mediated by three different pathways during synaptic transmission at a calyx-type synapse.
1998,
Pubmed
Borst,
In vivo imaging of calcium accumulation in fly interneurons as elicited by visual motion stimulation.
1992,
Pubmed
Broser,
Nonlinear anisotropic diffusion filtering of three-dimensional image data from two-photon microscopy.
2004,
Pubmed
Burnashev,
Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes.
1995,
Pubmed
Charpak,
Odor-evoked calcium signals in dendrites of rat mitral cells.
2001,
Pubmed
Cohen-Cory,
Neurotrophic regulation of retinal ganglion cell synaptic connectivity: from axons and dendrites to synapses.
2004,
Pubmed
,
Xenbase
Denk,
Two-photon laser scanning fluorescence microscopy.
1990,
Pubmed
Euler,
Directionally selective calcium signals in dendrites of starburst amacrine cells.
2002,
Pubmed
Ewald,
Roles of NR2A and NR2B in the development of dendritic arbor morphology in vivo.
2008,
Pubmed
,
Xenbase
Frick,
LTP is accompanied by an enhanced local excitability of pyramidal neuron dendrites.
2004,
Pubmed
Govindarajan,
A clustered plasticity model of long-term memory engrams.
2006,
Pubmed
Haas,
Single-cell electroporation for gene transfer in vivo.
2001,
Pubmed
,
Xenbase
Harris,
Dendritic plasticity in mouse barrel cortex following postnatal vibrissa follicle damage.
1981,
Pubmed
Harvey,
Locally dynamic synaptic learning rules in pyramidal neuron dendrites.
2007,
Pubmed
Hausselt,
A dendrite-autonomous mechanism for direction selectivity in retinal starburst amacrine cells.
2007,
Pubmed
Häusser,
Diversity and dynamics of dendritic signaling.
2000,
Pubmed
Häusser,
Dendrites: bug or feature?
2003,
Pubmed
Helmchen,
In vivo dendritic calcium dynamics in deep-layer cortical pyramidal neurons.
1999,
Pubmed
Holt,
Order in the initial retinotectal map in Xenopus: a new technique for labelling growing nerve fibres.
1983,
Pubmed
,
Xenbase
Isaacson,
Olfactory reciprocal synapses: dendritic signaling in the CNS.
1998,
Pubmed
Kampa,
Dendritic mechanisms controlling spike-timing-dependent synaptic plasticity.
2007,
Pubmed
Katz,
Relationships between segregated afferents and postsynaptic neurones in the optic tectum of three-eyed frogs.
1988,
Pubmed
Kitamura,
Targeted patch-clamp recordings and single-cell electroporation of unlabeled neurons in vivo.
2008,
Pubmed
Konur,
Calcium signaling and the control of dendritic development.
2005,
Pubmed
Larkum,
Synaptic clustering by dendritic signalling mechanisms.
2008,
Pubmed
Lohmann,
Local calcium transients regulate the spontaneous motility of dendritic filopodia.
2005,
Pubmed
Losonczy,
Integrative properties of radial oblique dendrites in hippocampal CA1 pyramidal neurons.
2006,
Pubmed
Losonczy,
Compartmentalized dendritic plasticity and input feature storage in neurons.
2008,
Pubmed
Luo,
Development of continuous and discrete neural maps.
2007,
Pubmed
Mann,
Topographic mapping in dorsoventral axis of the Xenopus retinotectal system depends on signaling through ephrin-B ligands.
2002,
Pubmed
,
Xenbase
McLaughlin,
Molecular gradients and development of retinotopic maps.
2005,
Pubmed
Mehta,
Cooperative LTP can map memory sequences on dendritic branches.
2004,
Pubmed
Mu,
Spike timing-dependent LTP/LTD mediates visual experience-dependent plasticity in a developing retinotectal system.
2006,
Pubmed
,
Xenbase
Nevian,
Calcium indicator loading of neurons using single-cell electroporation.
2007,
Pubmed
Niell,
Functional imaging reveals rapid development of visual response properties in the zebrafish tectum.
2005,
Pubmed
O'Rourke,
Dynamic aspects of retinotectal map formation revealed by a vital-dye fiber-tracing technique.
1986,
Pubmed
,
Xenbase
Poirazi,
Impact of active dendrites and structural plasticity on the memory capacity of neural tissue.
2001,
Pubmed
Pratt,
Development and spike timing-dependent plasticity of recurrent excitation in the Xenopus optic tectum.
2008,
Pubmed
,
Xenbase
Rall,
Dendrodendritic synaptic pathway for inhibition in the olfactory bulb.
1966,
Pubmed
Ruthazer,
Insights into activity-dependent map formation from the retinotectal system: a middle-of-the-brain perspective.
2004,
Pubmed
Sakaguchi,
Map formation in the developing Xenopus retinotectal system: an examination of ganglion cell terminal arborizations.
1985,
Pubmed
,
Xenbase
Sanchez,
BDNF increases synapse density in dendrites of developing tectal neurons in vivo.
2006,
Pubmed
,
Xenbase
Schiller,
NMDA spikes in basal dendrites of cortical pyramidal neurons.
2000,
Pubmed
Schmidt,
Activity-driven sharpening of the retinotectal projection: the search for retrograde synaptic signaling pathways.
2004,
Pubmed
Schneggenburger,
Fractional contribution of calcium to the cation current through glutamate receptor channels.
1993,
Pubmed
Segev,
Untangling dendrites with quantitative models.
2000,
Pubmed
Sin,
Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases.
2002,
Pubmed
,
Xenbase
Sjöström,
Dendritic excitability and synaptic plasticity.
2008,
Pubmed
Sorensen,
The level and integrity of synaptic input regulates dendrite structure.
2006,
Pubmed
Svoboda,
In vivo dendritic calcium dynamics in neocortical pyramidal neurons.
1997,
Pubmed
Tao,
Emergence of input specificity of ltp during development of retinotectal connections in vivo.
2001,
Pubmed
,
Xenbase
Vislay-Meltzer,
Spatiotemporal specificity of neuronal activity directs the modification of receptive fields in the developing retinotectal system.
2006,
Pubmed
,
Xenbase
Waters,
Caught on film: the secret lives of dendrites in the tadpole optic tectum.
2009,
Pubmed
,
Xenbase
Waters,
Supralinear Ca2+ influx into dendritic tufts of layer 2/3 neocortical pyramidal neurons in vitro and in vivo.
2003,
Pubmed
Wong,
Activity-dependent regulation of dendritic growth and patterning.
2002,
Pubmed
Wu,
Maturation of a central glutamatergic synapse.
1996,
Pubmed
,
Xenbase
Zelles,
Branch-specific Ca2+ influx from Na+-dependent dendritic spikes in olfactory granule cells.
2006,
Pubmed
Zhang,
Visual input induces long-term potentiation of developing retinotectal synapses.
2000,
Pubmed
,
Xenbase
Zhang,
A critical window for cooperation and competition among developing retinotectal synapses.
1998,
Pubmed
,
Xenbase
Zucker,
Calcium- and activity-dependent synaptic plasticity.
1999,
Pubmed