Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-30067
J Cell Biol 1983 Oct 01;974:1261-5.
Show Gene links Show Anatomy links

Nuclear exclusion of transcription factor IIIA and the 42s particle transfer RNA-binding protein in Xenopus oocytes: a possible mechanism for gene control?

Mattaj IW , Lienhard S , Zeller R , DeRobertis EM .


???displayArticle.abstract???
The intracellular location of 7S and 42S RNP particles in Xenopus oocytes has been determined by immunohistochemistry. Using antibodies directed against the 48-mol-wt protein component of the 42S particle and against transcription factor IIIA, the protein moiety of the 7S particle, we show that these ribonucleoprotein particles are detectable only in the oocyte cytoplasm, being excluded from the nucleus. The mechanism of this nuclear exclusion, and its possible significance in the regulation of 5S RNA gene expression, are discussed.

???displayArticle.pubmedLink??? 6413512
???displayArticle.pmcLink??? PMC2112615




References [+] :
Anderson, Sequence organization of the poly(A) RNA synthesized and accumulated in lampbrush chromosome stage Xenopus laevis oocytes. 1982, Pubmed, Xenbase