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Regulation of voltage dependence of the KAT1 channel by intracellular factors.
Hoshi T
.
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The KAT1 channel is a hyperpolarization-activated K+ channel cloned from the higher plant Arabidopsis. The deduced amino acid sequence suggests that its structural organization is similar to that of the Shaker-like K+ channel activated by depolarization. Electrophysiological properties of the KAT1 channel expressed in Xenopus oocytes indicate that voltage-dependent activation of the KAT1 channel is not caused by the divalent ion block and that it is intrinsic to the channel. Activity of the KAT1 channel progressively decreases upon patch excision. This rundown of the channel is accompanied by a large shift in the voltage dependence of the channel to a more negative direction. The voltage dependence is also regulated by pH, ATP, and cGMP.
Anderson,
Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cerevisiae.
1992, Pubmed
Anderson,
Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cerevisiae.
1992,
Pubmed
Anumonwo,
Electrophysiology of single heart cells from the rabbit tricuspid valve.
1990,
Pubmed
Bean,
Whole-cell recording of calcium channel currents.
1992,
Pubmed
Brüggemann,
Ether-à-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP.
1993,
Pubmed
,
Xenbase
Burton,
Sensitivity to flow of intrinsic gating in inwardly rectifying potassium channel from mammalian skeletal muscle.
1990,
Pubmed
Cohen,
Internal and external K+ help gate the inward rectifier.
1989,
Pubmed
Guy,
Similarities in amino acid sequences of Drosophila eag and cyclic nucleotide-gated channels.
1991,
Pubmed
Ho,
Cloning and expression of an inwardly rectifying ATP-regulated potassium channel.
1993,
Pubmed
,
Xenbase
Horn,
Prevention of rundown in electrophysiological recording.
1992,
Pubmed
Hoshi,
Biophysical and molecular mechanisms of Shaker potassium channel inactivation.
1990,
Pubmed
,
Xenbase
Hoshi,
Shaker potassium channel gating. I: Transitions near the open state.
1994,
Pubmed
,
Xenbase
Kramer,
Patch cramming: monitoring intracellular messengers in intact cells with membrane patches containing detector ion channels.
1990,
Pubmed
Kubo,
Primary structure and functional expression of a mouse inward rectifier potassium channel.
1993,
Pubmed
,
Xenbase
Kubo,
Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel.
1993,
Pubmed
,
Xenbase
MacKinnon,
Determination of the subunit stoichiometry of a voltage-activated potassium channel.
1991,
Pubmed
,
Xenbase
Marom,
Mechanism and modulation of inactivation of the Kv3 potassium channel.
1993,
Pubmed
,
Xenbase
Matsuda,
Magnesium gating of the inwardly rectifying K+ channel.
1991,
Pubmed
Pennefather,
Origin of the potassium and voltage dependence of the cardiac inwardly rectifying K-current (IK1).
1992,
Pubmed
Ruppersberg,
Heteromultimeric channels formed by rat brain potassium-channel proteins.
1990,
Pubmed
,
Xenbase
Salkoff,
An essential 'set' of K+ channels conserved in flies, mice and humans.
1992,
Pubmed
,
Xenbase
Schachtman,
Expression of an inward-rectifying potassium channel by the Arabidopsis KAT1 cDNA.
1992,
Pubmed
,
Xenbase
Schoppa,
The size of gating charge in wild-type and mutant Shaker potassium channels.
1992,
Pubmed
Schroeder,
K+ transport properties of K+ channels in the plasma membrane of Vicia faba guard cells.
1988,
Pubmed
Schroeder,
Voltage dependence of K channels in guard-cell protoplasts.
1987,
Pubmed
Sentenac,
Cloning and expression in yeast of a plant potassium ion transport system.
1992,
Pubmed
Warmke,
A distinct potassium channel polypeptide encoded by the Drosophila eag locus.
1991,
Pubmed
Zagotta,
Shaker potassium channel gating. III: Evaluation of kinetic models for activation.
1994,
Pubmed
,
Xenbase
Zagotta,
Gating of single Shaker potassium channels in Drosophila muscle and in Xenopus oocytes injected with Shaker mRNA.
1989,
Pubmed
,
Xenbase
Zagotta,
Shaker potassium channel gating. II: Transitions in the activation pathway.
1994,
Pubmed
,
Xenbase
Zagotta,
Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB.
1990,
Pubmed
,
Xenbase
