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EMBO J
1991 Mar 01;103:599-606. doi: 10.1002/j.1460-2075.1991.tb07987.x.
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Transcription of the Xenopus laevis selenocysteine tRNA(Ser)Sec gene: a system that combines an internal B box and upstream elements also found in U6 snRNA genes.
Carbon P
,
Krol A
.
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The transcription mode of the Xenopus tRNA(Ser)Sec gene by RNA polymerase III was deciphered by injection of mutant templates into Xenopus oocyte nuclei. tRNA(Ser)Sec represents the paradigm of a new class of RNA polymerase III genes combining tRNA and U snRNA gene regulatory elements. Its promoter is tripartite, constituted by two upstream elements, a PSE and a TATA motif that are interchangeable with those of U6 snRNA genes and an internal box B as in other tRNAs. The B box enables the transcription level dependent on the upstream promoter to be increased. Data obtained indicate that U1 snRNA (Pol II) and tRNA(Ser)Sec (Pol III) genes share at least one transcription factor, implying that the border between transcription systems is less tight than expected.
Bark,
A distant enhancer element is required for polymerase III transcription of a U6 RNA gene.
, Pubmed,
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Bark,
A distant enhancer element is required for polymerase III transcription of a U6 RNA gene.
,
Pubmed
,
Xenbase
Brow,
Transcription of a yeast U6 snRNA gene requires a polymerase III promoter element in a novel position.
1990,
Pubmed
Cannon,
Functions of and interactions between the A and B blocks in adenovirus type 2-specific VARNA1 gene.
1986,
Pubmed
Carbon,
A common octamer motif binding protein is involved in the transcription of U6 snRNA by RNA polymerase III and U2 snRNA by RNA polymerase II.
1987,
Pubmed
,
Xenbase
Ciliberto,
Transcription by RNA polymerase III.
1983,
Pubmed
Das,
Upstream regulatory elements are necessary and sufficient for transcription of a U6 RNA gene by RNA polymerase III.
1988,
Pubmed
,
Xenbase
Diamond,
Structure and properties of a bovine liver UGA suppressor serine tRNA with a tryptophan anticodon.
1981,
Pubmed
Galli,
Two conserved sequence blocks within eukaryotic tRNA genes are major promoter elements.
1981,
Pubmed
,
Xenbase
Geiduschek,
Transcription by RNA polymerase III.
1988,
Pubmed
Hatfield,
Characterization and nucleotide sequence of a chicken gene encoding an opal suppressor tRNA and its flanking DNA segments.
1983,
Pubmed
Heider,
Occurrence and functional compatibility within Enterobacteriaceae of a tRNA species which inserts selenocysteine into protein.
1989,
Pubmed
Howe,
Epstein-Barr virus small RNA (EBER) genes: unique transcription units that combine RNA polymerase II and III promoter elements.
1989,
Pubmed
Kassavetis,
S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors.
1990,
Pubmed
Kleinert,
Expression of a human 7S K RNA gene in vivo requires a novel pol III upstream element.
1990,
Pubmed
Krol,
The two embryonic U1 RNA genes of Xenopus laevis have both common and gene-specific transcription signals.
1985,
Pubmed
,
Xenbase
Krol,
Xenopus tropicalis U6 snRNA genes transcribed by Pol III contain the upstream promoter elements used by Pol II dependent U snRNA genes.
1987,
Pubmed
,
Xenbase
Kunkel,
Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used.
1988,
Pubmed
Larson,
A short 5' flanking region containing conserved sequences is required for silkworm alanine tRNA gene activity.
1983,
Pubmed
Lee,
Transcription of Xenopus selenocysteine tRNA Ser (formerly designated opal suppressor phosphoserine tRNA) gene is directed by multiple 5'-extragenic regulatory elements.
1989,
Pubmed
,
Xenbase
Lee,
Selenocysteine tRNA[Ser]Sec gene is ubiquitous within the animal kingdom.
1990,
Pubmed
,
Xenbase
Lee,
Unique pathway of expression of an opal suppressor phosphoserine tRNA.
1987,
Pubmed
,
Xenbase
Leinfelder,
Gene for a novel tRNA species that accepts L-serine and cotranslationally inserts selenocysteine.
1988,
Pubmed
Lobo,
A 7 bp mutation converts a human RNA polymerase II snRNA promoter into an RNA polymerase III promoter.
1989,
Pubmed
Lobo,
cis-acting elements required for RNA polymerase II and III transcription in the human U2 and U6 snRNA promoters.
1990,
Pubmed
Mattaj,
Changing the RNA polymerase specificity of U snRNA gene promoters.
1988,
Pubmed
,
Xenbase
Mattaj,
Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes.
1983,
Pubmed
,
Xenbase
Moenne,
The U6 gene of Saccharomyces cerevisiae is transcribed by RNA polymerase C (III) in vivo and in vitro.
1990,
Pubmed
Murphy,
Purified octamer binding transcription factors stimulate RNA polymerase III--mediated transcription of the 7SK RNA gene.
1989,
Pubmed
Murphy,
Common mechanisms of promoter recognition by RNA polymerases II and III.
1989,
Pubmed
Murphy,
A sequence upstream from the coding region is required for the transcription of the 7SK RNA genes.
1986,
Pubmed
Murphy,
The in vitro transcription of the 7SK RNA gene by RNA polymerase III is dependent only on the presence of an upstream promoter.
1987,
Pubmed
Neuman de Vegvar,
Initiation and termination of human U1 RNA transcription requires the concerted action of multiple flanking elements.
1989,
Pubmed
,
Xenbase
Ohshima,
Nucleotide sequences of mouse genomic loci including a gene or pseudogene for U6 (4.8S) nuclear RNA.
1981,
Pubmed
O'Neill,
A human opal suppressor tRNA gene and pseudogene.
1985,
Pubmed
Parry,
The Xenopus U2 gene PSE is a single, compact, element required for transcription initiation and 3' end formation.
1989,
Pubmed
,
Xenbase
Parry,
Positive and negative functional interactions between promoter elements from different classes of RNA polymerase III-transcribed genes.
1990,
Pubmed
,
Xenbase
Perez-Stable,
Distinctive sequence organization and functional programming of an Alu repeat promoter.
1984,
Pubmed
Pieler,
The 5S gene internal control region is composed of three distinct sequence elements, organized as two functional domains with variable spacing.
1987,
Pubmed
,
Xenbase
Pratt,
Conserved sequences in both coding and 5' flanking regions of mammalian opal suppressor tRNA genes.
1985,
Pubmed
Ruggiero-Lopez,
Participation of an endogenous inhibitor of fucosyltransferase activities in the developmental regulation of intestinal fucosylation processes.
1991,
Pubmed
Selker,
An upstream signal is required for in vitro transcription of Neurospora 5S RNA genes.
1986,
Pubmed
Sharp,
Structure and transcription of eukaryotic tRNA genes.
1985,
Pubmed
Simmen,
Complex requirements for RNA polymerase III transcription of the Xenopus U6 promoter.
1990,
Pubmed
,
Xenbase
Sollner-Webb,
Surprises in polymerase III transcription.
1988,
Pubmed
Ullu,
Upstream sequences modulate the internal promoter of the human 7SL RNA gene.
,
Pubmed