XB-ART-47844
Dev Cell
2013 Oct 14;271:1-2. doi: 10.1016/j.devcel.2013.09.027.
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Sculpting the nucleus with dynamic microtubules.
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How nuclear morphology is regulated during development and disease remains poorly understood. In this issue of Developmental Cell, using a pronuclear assembly assay, Xue et al. (2013) demonstrate that Dppa2, a chromatin-bound microtubule regulator, controls both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.
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Species referenced: Xenopus
Genes referenced: dppa2
References [+] :
Carmena,
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis.
2012, Pubmed