Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-28020
Dev Biol 1987 Aug 01;1222:586-8.
Show Gene links Show Anatomy links

Acceleration of the rate of processing of 40 S pre-rRNA during Xenopus laevis embryogenesis.

Shiokawa K , Fu Y , Yamana K .


???displayArticle.abstract???
Processing of 40 S pre-rRNA into 18 and 28 S mature rRNAs was studied in Xenopus embryonic cells by pulse-chase experiments using actinomycin D as a transcription-inhibitor. Gel electrophoretic analyses revealed that the rate of processing was accelerated due to a shortening of the half-life of 40 S pre-rRNA from 19 min at the gastrula stage to 9 min at and after the neurula stage. The step under developmental control appeared to be the cleavage of 40 S pre-rRNA into 18 S rRNA and the 34 S rRNA intermediate, since the time interval between the first detection of labeled 40 S pre-rRNA and 18 S rRNA was significantly shortened as development proceeded.

???displayArticle.pubmedLink??? 3647911
???displayArticle.link??? Dev Biol