Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-168
Cell 2006 Jun 30;1257:1347-60. doi: 10.1016/j.cell.2006.06.011.
Show Gene links Show Anatomy links

A protein kinase, interacting with two calcineurin B-like proteins, regulates K+ transporter AKT1 in Arabidopsis.

Xu J , Li HD , Chen LQ , Wang Y , Liu LL , He L , Wu WH .


???displayArticle.abstract???
Potassium is an essential mineral element for plant growth and development. Although it is known that plants absorb and transport K+ through membrane transporters, it remains unclear how these transporters are regulated. Here we show that the protein kinase CIPK23, encoded by the LKS1 gene, regulates K+ uptake under low-K+ conditions. Lesion of LKS1 significantly reduced K+ uptake and caused leaf chlorosis and growth inhibition, whereas overexpression of LKS1 significantly enhanced K+ uptake and tolerance to low K+. We demonstrate that CIPK23 directly phosphorylates the K+ transporter AKT1 and further find that CIPK23 is activated by the binding of two calcineurin B-like proteins, CBL1 and CBL9. We propose a model in which the CBL1/9-CIPK23 pathway ensures activation of AKT1 and enhanced K+ uptake under low-K+ conditions.

???displayArticle.pubmedLink??? 16814720
???displayArticle.link??? Cell


Species referenced: Xenopus laevis
Genes referenced: akt1 ppp3ca

References :
Hedrich, Calcium signaling networks channel plant K+ uptake. 2006, Pubmed