Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Sequences involved in accurate and efficient transcription of human c-myc genes microinjected into frog oocytes.
Nishikura K
.
???displayArticle.abstract???
By microinjecting a series of deletion mutant constructs into Xenopus laevis oocytes, transcriptional control regions, two promoters, of the human c-myc gene were defined. In the case of the first promoter, sequences between -60 and -37 relative to the transcription start site contained an element essential for promoter activity. In the case of the second promoter, sequences between -66 and -56 relative to the initiation site appeared to be involved in accurate and efficient transcription. In both cases, the region identified as the essential promoter element contained GGGCGG or GGCGGG,GC box-like sequences, suggesting that c-myc gene promoter activity may be controlled by transcription factor Sp1 binding in the microinjected oocytes.
Battey,
The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma.
1983, Pubmed
Battey,
The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma.
1983,
Pubmed
Berk,
Spliced early mRNAs of simian virus 40.
1978,
Pubmed
Bernard,
Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.
1983,
Pubmed
Blanchard,
c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors.
,
Pubmed
Breathnach,
Organization and expression of eucaryotic split genes coding for proteins.
1981,
Pubmed
Brown,
High-fidelity transcription of 5S DNA injected into Xenopus oocytes.
1977,
Pubmed
,
Xenbase
Campisi,
Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation.
1984,
Pubmed
Cortese,
Cloning of nematode tRNA genes and their expression in the frog oocyte.
1978,
Pubmed
,
Xenbase
Dani,
Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells.
1985,
Pubmed
Dony,
Post-transcriptional control of myc and p53 expression during differentiation of the embryonal carcinoma cell line F9.
,
Pubmed
Dush,
Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement.
1985,
Pubmed
Dynan,
Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter.
,
Pubmed
Dyson,
Chromatin structure around the c-myc gene in Burkitt lymphomas with upstream and downstream translocation points.
1985,
Pubmed
Etkin,
The synthesis of authentic sea urchin transcriptional and translational products by sea urchin histone genes injected into Xenopus laevis oocytes.
1980,
Pubmed
,
Xenbase
Gerhart,
Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs.
1984,
Pubmed
,
Xenbase
Gidoni,
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions.
1985,
Pubmed
Gidoni,
Multiple specific contacts between a mammalian transcription factor and its cognate promoters.
,
Pubmed
Greenberg,
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene.
,
Pubmed
Gurdon,
Injected nuclei in frog oocytes: fate, enlargement, and chromatin dispersal.
1976,
Pubmed
,
Xenbase
Jones,
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro.
1985,
Pubmed
Jones,
Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro.
,
Pubmed
Kelly,
Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor.
1983,
Pubmed
Klein,
Evolution of tumours and the impact of molecular oncology.
,
Pubmed
Kressmann,
Transcription of cloned tRNA gene fragments and subfragments injected into the oocyte nucleus of Xenopus laevis.
1978,
Pubmed
,
Xenbase
Leder,
Translocations among antibody genes in human cancer.
1983,
Pubmed
Ley,
RNA processing errors in patients with beta-thalassemia.
1982,
Pubmed
Melton,
Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.
1984,
Pubmed
Moss,
A transcriptional function for the repetitive ribosomal spacer in Xenopus laevis.
,
Pubmed
,
Xenbase
Müller,
Induction of c-fos gene and protein by growth factors precedes activation of c-myc.
,
Pubmed
Nishikura,
RNA processing in microinjected Xenopus oocytes. Sequential addition of base modifications in the spliced transfer RNA.
1981,
Pubmed
,
Xenbase
Nishikura,
Accurate and efficient transcription of human c-myc genes injected into Xenopus laevis oocytes.
1985,
Pubmed
,
Xenbase
Probst,
Expression of sea urchin histone genes in the oocyte of Xenopus laevis.
1979,
Pubmed
,
Xenbase
Ratner,
Complete nucleotide sequence of the AIDS virus, HTLV-III.
,
Pubmed
Reeder,
Spacer regulation of Xenopus ribosomal gene transcription: competition in oocytes.
1983,
Pubmed
,
Xenbase
Reitsma,
Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite.
,
Pubmed
Reynolds,
HMG CoA reductase: a negatively regulated gene with unusual promoter and 5' untranslated regions.
1984,
Pubmed
Richards,
Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids.
1984,
Pubmed
Sanchez-Pescador,
Nucleotide sequence and expression of an AIDS-associated retrovirus (ARV-2).
1985,
Pubmed
Sanger,
DNA sequencing with chain-terminating inhibitors.
1977,
Pubmed
Siebenlist,
Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma.
1984,
Pubmed
Valerio,
Adenosine deaminase: characterization and expression of a gene with a remarkable promoter.
1985,
Pubmed
Wickens,
Post-transcriptional processing of simian virus 40 late transcripts in injected frog oocytes.
1983,
Pubmed
,
Xenbase
