XB-ART-27978
J Mol Biol
1987 Sep 05;1971:147-8. doi: 10.1016/0022-2836(87)90617-6.
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DNA-binding fingers encoded by a trypanosome retroposon.
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A Trypanosoma brucei repeated DNA element (TRS-1, for trypanosome repeated sequence), which seems transposable, may encode a 1651 amino acid polypeptide showing homology with reverse transcriptase. This polypeptide would also carry a DNA-binding domain, as suggested by the presence of five DNA-binding "fingers" homologous to those of the transcription factor TFIIIA of Xenopus laevis and retroviral DNA-binding proteins.
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Species referenced: Xenopus laevis
Genes referenced: gtf3a