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XB-ART-8166
Dev Genes Evol 2001 Sep 01;2118-9:442-4. doi: 10.1007/s004270100168.
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Identification and expression of zebrafish Iroquois homeobox gene irx1.

Cheng CW , Hui C , Strähle U , Cheng SH .


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Iroquois homeoproteins are prepatterning factors that positively regulate proneural genes and control neurogenesis. We have identified a zebrafish Iroquois gene, irx1, which is highly homologous to Xenopus Xiro1, Gallus c-Irx1 and mouse Irx1. Expression of irx1 was initially detected at the bud stage. By 16 h post-fertilization (hpf), irx1 expression was exclusively limited to the prospective midbrain and hindbrain. By 24 hpf, irx1 expression was clearly detected in the acousticovestibual ganglia, tectum, tegmentum, cerebellum and rhombomere 1 but not in rhombomere 2 or mid-hindbrain boundary.

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Species referenced: Xenopus
Genes referenced: irx1