Zinski J , Tajer B , Mullins MC .

R01 GM056326 NIGMS NIH HHS , T32 HD083185 NICHD NIH HHS , F32 HD008318 NICHD NIH HHS

Aamar, Sox17 and chordin are required for formation of Kupffer's vesicle and left-right asymmetry determination in zebrafish. 2010, Pubmed

Aamar, Sox17 and chordin are required for formation of Kupffer's vesicle and left-right asymmetry determination in zebrafish. 2010, Pubmed
Abdollah, TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling. 1997, Pubmed
Abe, Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection. 2016, Pubmed
Abe, The origin of the bifurcated axial skeletal system in the twin-tail goldfish. 2014, Pubmed
Adachi, Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer. 1999, Pubmed
Adams, Early, H+-V-ATPase-dependent proton flux is necessary for consistent left-right patterning of non-mammalian vertebrates. 2006, Pubmed , Xenbase
Adamska, Wnt and TGF-beta expression in the sponge Amphimedon queenslandica and the origin of metazoan embryonic patterning. 2007, Pubmed
Agathon, The molecular nature of the zebrafish tail organizer. 2003, Pubmed
Agathon, Morpholino knock-down of antivin1 and antivin2 upregulates nodal signaling. 2001, Pubmed
Agius, Endodermal Nodal-related signals and mesoderm induction in Xenopus. 2000, Pubmed , Xenbase
Albano, Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain. 1994, Pubmed
Albertson, Zebrafish acvr2a and acvr2b exhibit distinct roles in craniofacial development. 2005, Pubmed
Alten, Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1. 2012, Pubmed
Amaya, FGF signalling in the early specification of mesoderm in Xenopus. 1993, Pubmed , Xenbase
Amaya, Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. 1991, Pubmed , Xenbase
Ambrosio, Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. 2008, Pubmed , Xenbase
Andersson, Synergistic interaction between Gdf1 and Nodal during anterior axis development. 2006, Pubmed
Andersson, Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development. 2007, Pubmed , Xenbase
Angerer, A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis. 2000, Pubmed , Xenbase
Antic, Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis. 2010, Pubmed , Xenbase
Aoki, Regulation of nodal signalling and mesendoderm formation by TARAM-A, a TGFbeta-related type I receptor. 2002, Pubmed
Armes, The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds. 1997, Pubmed , Xenbase
Arnold, Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. 2006, Pubmed , Xenbase
Arnold, Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. 2009, Pubmed
Aw, The ATP-sensitive K(+)-channel (K(ATP)) controls early left-right patterning in Xenopus and chick embryos. 2010, Pubmed , Xenbase
Aykul, New Ligand Binding Function of Human Cerberus and Role of Proteolytic Processing in Regulating Ligand-Receptor Interactions and Antagonist Activity. 2016, Pubmed
Aykul, Human Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypes. 2015, Pubmed
Bachiller, The organizer factors Chordin and Noggin are required for mouse forebrain development. 2000, Pubmed
Bachiller, The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. 2003, Pubmed
Bae, Siamois and Twin are redundant and essential in formation of the Spemann organizer. 2011, Pubmed , Xenbase
Baker, Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart. 2008, Pubmed
Bakkers, Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm. 2002, Pubmed
Bakkers, Zebrafish as a model to study cardiac development and human cardiac disease. 2011, Pubmed
Barth, fsi zebrafish show concordant reversal of laterality of viscera, neuroanatomy, and a subset of behavioral responses. 2005, Pubmed
Bassett, Understanding functional miRNA-target interactions in vivo by site-specific genome engineering. 2014, Pubmed
Basu, Cilia multifunctional organelles at the center of vertebrate left-right asymmetry. 2008, Pubmed , Xenbase
Bates, Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling. 2013, Pubmed , Xenbase
Bauer, The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. 2001, Pubmed
Bayramov, Novel functions of Noggin proteins: inhibition of Activin/Nodal and Wnt signaling. 2011, Pubmed , Xenbase
Beck, Extraembryonic proteases regulate Nodal signalling during gastrulation. 2002, Pubmed
Beddington, Axis development and early asymmetry in mammals. 1999, Pubmed
Bell, Cell fate specification and competence by Coco, a maternal BMP, TGFbeta and Wnt inhibitor. 2003, Pubmed , Xenbase
Belo, Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development. 2000, Pubmed , Xenbase
Belo, Generating asymmetries in the early vertebrate embryo: the role of the Cerberus-like family. 2009, Pubmed , Xenbase
Belting, Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression. 2011, Pubmed
Ben-Haim, The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. 2006, Pubmed
Bennett, Maternal nodal and zebrafish embryogenesis. 2007, Pubmed
Ben-Zvi, Scaling of the BMP activation gradient in Xenopus embryos. 2008, Pubmed , Xenbase
Ben-Zvi, Scaling of dorsal-ventral patterning in the Xenopus laevis embryo. 2014, Pubmed , Xenbase
Beppu, BMP type II receptor is required for gastrulation and early development of mouse embryos. 2000, Pubmed
Bertocchini, The hypoblast of the chick embryo positions the primitive streak by antagonizing nodal signaling. 2002, Pubmed , Xenbase
Biehs, The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm. 1996, Pubmed , Xenbase
Bijakowski, Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases. 2012, Pubmed , Xenbase
Birsoy, Vg 1 is an essential signaling molecule in Xenopus development. 2006, Pubmed , Xenbase
Bisgrove, Regulation of midline development by antagonism of lefty and nodal signaling. 1999, Pubmed
Bisgrove, Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis. 2005, Pubmed , Xenbase
Blader, Cleavage of the BMP-4 antagonist chordin by zebrafish tolloid. 1997, Pubmed , Xenbase
Blitz, Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis. 2003, Pubmed , Xenbase
Blitz, Is chordin a long-range- or short-range-acting factor? Roles for BMP1-related metalloproteases in chordin and BMP4 autofeedback loop regulation. 2000, Pubmed , Xenbase
Blum, Xenopus, an ideal model system to study vertebrate left-right asymmetry. 2009, Pubmed , Xenbase
Blum, Ciliation and gene expression distinguish between node and posterior notochord in the mammalian embryo. 2007, Pubmed , Xenbase
Blum, The evolution and conservation of left-right patterning mechanisms. 2014, Pubmed , Xenbase
Blum, Symmetry breakage in the vertebrate embryo: when does it happen and how does it work? 2014, Pubmed , Xenbase
Borges, Goosecoid and cerberus-like do not interact during mouse embryogenesis. 2002, Pubmed
Borges, The BMP antagonists cerberus-like and noggin do not interact during mouse forebrain development. 2001, Pubmed
Borovina, Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia. 2010, Pubmed
Bourillot, A changing morphogen gradient is interpreted by continuous transduction flow. 2002, Pubmed , Xenbase
Bouwmeester, Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. 1996, Pubmed , Xenbase
Branam, Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis. 2010, Pubmed
Branford, Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation. 2002, Pubmed , Xenbase
Branford, Regulation of gut and heart left-right asymmetry by context-dependent interactions between xenopus lefty and BMP4 signaling. 2000, Pubmed , Xenbase
Branney, Characterisation of the fibroblast growth factor dependent transcriptome in early development. 2009, Pubmed , Xenbase
Brennan, Nodal activity in the node governs left-right asymmetry. 2002, Pubmed
Brennan, Nodal signalling in the epiblast patterns the early mouse embryo. 2001, Pubmed
Brody, Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice. 2000, Pubmed
Burdine, Antagonistic interactions in the zebrafish midline prior to the emergence of asymmetric gene expression are important for left-right patterning. 2016, Pubmed
Campione, The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping. 1999, Pubmed , Xenbase
Canty, A complete domain structure of Drosophila tolloid is required for cleavage of short gastrulation. 2006, Pubmed
Cao, fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos. 2004, Pubmed
Carmany-Rampey, Single-cell internalization during zebrafish gastrulation. 2001, Pubmed
Carnac, The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm. 1996, Pubmed , Xenbase
Carron, Specification of anteroposterior axis by combinatorial signaling during Xenopus development. 2016, Pubmed , Xenbase
Cha, Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation. 2008, Pubmed , Xenbase
Cha, Cooperative non-cell and cell autonomous regulation of Nodal gene expression and signaling by Lefty/Antivin and Brachyury in Xenopus. 2006, Pubmed , Xenbase
Chamorro, FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development. 2005, Pubmed , Xenbase
Chang, Regulation of nodal and BMP signaling by tomoregulin-1 (X7365) through novel mechanisms. 2003, Pubmed , Xenbase
Chang, Smad5 is essential for left-right asymmetry in mice. 2000, Pubmed
Chang, Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. 1999, Pubmed
Chang, Xenopus GDF6, a new antagonist of noggin and a partner of BMPs. 1999, Pubmed , Xenbase
Chang, Smad5 is required for mouse primordial germ cell development. 2001, Pubmed
Chang, Twisted gastrulation can function as a BMP antagonist. 2001, Pubmed , Xenbase
Chen, Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry. 1998, Pubmed
Chen, The zebrafish Nodal signal Squint functions as a morphogen. 2001, Pubmed
Chen, Two modes by which Lefty proteins inhibit nodal signaling. 2004, Pubmed , Xenbase
Chen, Lefty proteins are long-range inhibitors of squint-mediated nodal signaling. 2002, Pubmed
Chen, Generation and characterization of Tmeff2 mutant mice. 2012, Pubmed
Chen, A transcriptional partner for MAD proteins in TGF-beta signalling. 1996, Pubmed , Xenbase
Cheng, Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. 2004, Pubmed , Xenbase
Cheng, EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. 2003, Pubmed , Xenbase
Cheng, The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus. 2000, Pubmed , Xenbase
Cheyette, Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation. 2002, Pubmed , Xenbase
Chi, A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development. 2011, Pubmed
Chiodelli, Heparan sulfate proteoglycans mediate the angiogenic activity of the vascular endothelial growth factor receptor-2 agonist gremlin. 2011, Pubmed
Chiu, Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program. 2014, Pubmed , Xenbase
Cho, BMP signal attenuates FGF pathway in anteroposterior neural patterning. 2013, Pubmed , Xenbase
Chocron, Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. 2007, Pubmed
Choi, Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. 2007, Pubmed
Chu, Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis. 2010, Pubmed
Church, Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7. 2015, Pubmed
Collart, The novel Smad-interacting protein Smicl regulates Chordin expression in the Xenopus embryo. 2005, Pubmed , Xenbase
Collavin, The secreted Frizzled-related protein Sizzled functions as a negative feedback regulator of extreme ventral mesoderm. 2003, Pubmed , Xenbase
Collignon, Relationship between asymmetric nodal expression and the direction of embryonic turning. 1996, Pubmed
Concha, A nodal signaling pathway regulates the laterality of neuroanatomical asymmetries in the zebrafish forebrain. 2000, Pubmed
Conlon, A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. 1994, Pubmed
Connors, The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo. 1999, Pubmed
Connors, Temporal and spatial action of tolloid (mini fin) and chordin to pattern tail tissues. 2006, Pubmed
Constam, SPC4/PACE4 regulates a TGFbeta signaling network during axis formation. 2000, Pubmed
Cooke, Dynamics of the control of body pattern in the development of Xenopus laevis. III. Timing and pattern after u.v. irradiation of the egg and after excision of presumptive head endo-mesoderm. 1985, Pubmed , Xenbase
Cooper, A cluster of noninvoluting endocytic cells at the margin of the zebrafish blastoderm marks the site of embryonic shield formation. 1996, Pubmed
Coucouvanis, BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo. 1999, Pubmed
Cui, Synergistic effects of Vg1 and Wnt signals in the specification of dorsal mesoderm and endoderm. 1996, Pubmed , Xenbase
Cunliffe, Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue. 1992, Pubmed , Xenbase
Dale, Secretion and mesoderm-inducing activity of the TGF-beta-related domain of Xenopus Vg1. 1993, Pubmed , Xenbase
Dale, Xolloid-related: a novel BMP1/Tolloid-related metalloprotease is expressed during early Xenopus development. 2002, Pubmed , Xenbase
Dal-Pra, Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity. 2006, Pubmed , Xenbase
D'Amico, Spatially distinct domains of cell behavior in the zebrafish organizer region. 1997, Pubmed , Xenbase
Danesh, BMP and BMP receptor expression during murine organogenesis. 2009, Pubmed
Danos, Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus. 1996, Pubmed , Xenbase
Davidson, The node of the mouse embryo. 2000, Pubmed
Davidson, Impact of node ablation on the morphogenesis of the body axis and the lateral asymmetry of the mouse embryo during early organogenesis. 1999, Pubmed
Davis, The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery. 2008, Pubmed
Davis, BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning. 2004, Pubmed
de Almeida, Unexpected activities of Smad7 in Xenopus mesodermal and neural induction. 2008, Pubmed , Xenbase
Degenkolbe, A GDF5 point mutation strikes twice--causing BDA1 and SYNS2. 2013, Pubmed
Deglincerti, Coco is a dual activity modulator of TGFβ signaling. 2015, Pubmed , Xenbase
De Groot, Expression patterns of follistatin and two follistatin-related proteins during mouse development. 2000, Pubmed
Delaune, Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition. 2005, Pubmed , Xenbase
Denes, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in bilateria. 2007, Pubmed
De Robertis, Evo-devo: variations on ancestral themes. 2008, Pubmed
De Robertis, A common plan for dorsoventral patterning in Bilateria. 1996, Pubmed , Xenbase
De Robertis, Dorsal-ventral patterning and neural induction in Xenopus embryos. 2004, Pubmed , Xenbase
De Robertis, The Chordin Morphogenetic Pathway. 2016, Pubmed , Xenbase
Dewulf, Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis. 1995, Pubmed
Dick, Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo. 2000, Pubmed
Dickmeis, Expression of the anti-dorsalizing morphogenetic protein gene in the zebrafish embryo. 2001, Pubmed , Xenbase
Di-Gregorio, BMP signalling inhibits premature neural differentiation in the mouse embryo. 2007, Pubmed
Ding, Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. 1998, Pubmed
Dionne, Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor beta antagonists. 2001, Pubmed , Xenbase
Dohrmann, Induction of axial mesoderm by zDVR-1, the zebrafish orthologue of Xenopus Vg1. 1996, Pubmed , Xenbase
Dorey, A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos. 2006, Pubmed , Xenbase
Dosch, Requirement for anti-dorsalizing morphogenetic protein in organizer patterning. 2000, Pubmed , Xenbase
Dougan, The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. 2003, Pubmed
Duboc, Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo. 2004, Pubmed
Duboc, Left-right asymmetry in the sea urchin embryo is regulated by nodal signaling on the right side. 2005, Pubmed
Dubrulle, Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. 2015, Pubmed
Dudley, A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. 1995, Pubmed
Dufort, The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. 1998, Pubmed
Dunn, Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo. 2004, Pubmed
Dupont, Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase. 2005, Pubmed , Xenbase
Dyson, The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. 1998, Pubmed , Xenbase
Ecochard, A novel TGF-beta-like gene, fugacin, specifically expressed in the Spemann organizer of Xenopus. 1995, Pubmed , Xenbase
Eimon, In Xenopus embryos, BMP heterodimers are not required for mesoderm induction, but BMP activity is necessary for dorsal/ventral patterning. 1999, Pubmed , Xenbase
Eivers, Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad. 2009, Pubmed
Engert, Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse. 2013, Pubmed
Episkopou, Induction of the mammalian node requires Arkadia function in the extraembryonic lineages. 2001, Pubmed , Xenbase
Erter, Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo. 2001, Pubmed , Xenbase
Erter, Zebrafish nodal-related 2 encodes an early mesendodermal inducer signaling from the extraembryonic yolk syncytial layer. 1998, Pubmed
Essner, Conserved function for embryonic nodal cilia. 2002, Pubmed , Xenbase
Essner, Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms. 2000, Pubmed , Xenbase
Essner, Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut. 2005, Pubmed
Esteves, BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanisms. 2014, Pubmed
Fan, Nodal signals mediate interactions between the extra-embryonic and embryonic tissues in zebrafish. 2007, Pubmed
Fan, The evolutionary origin of nodal-related genes in teleosts. 2007, Pubmed
Fauny, The entire zebrafish blastula-gastrula margin acts as an organizer dependent on the ratio of Nodal to BMP activity. 2009, Pubmed
Faure, Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development. 2000, Pubmed , Xenbase
Feijen, Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins. 1994, Pubmed
Fekany-Lee, The homeobox gene bozozok promotes anterior neuroectoderm formation in zebrafish through negative regulation of BMP2/4 and Wnt pathways. 2000, Pubmed
Feldman, Nodal-related signals establish mesendodermal fate and trunk neural identity in zebrafish. 2000, Pubmed , Xenbase
Feldman, Lefty antagonism of Squint is essential for normal gastrulation. 2002, Pubmed
Feldman, Morpholino phenocopies of sqt, oep, and ntl mutations. 2001, Pubmed
Feldman, Zebrafish organizer development and germ-layer formation require nodal-related signals. 1998, Pubmed
Ferguson, Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. 1992, Pubmed
Finley, The mouse secreted frizzled-related protein 5 gene is expressed in the anterior visceral endoderm and foregut endoderm during early post-implantation development. 2003, Pubmed
Fisher, Loss of cerebum function ventralizes the zebrafish embryo. 1997, Pubmed , Xenbase
Fleming, A role for Vg1/Nodal signaling in specification of the intermediate mesoderm. 2013, Pubmed
Fletcher, The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus. 2008, Pubmed , Xenbase
Flores, Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish. 2008, Pubmed
Francescatto, The activation of membrane targeted CaMK-II in the zebrafish Kupffer's vesicle is required for left-right asymmetry. 2010, Pubmed
Francois, Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. 1994, Pubmed
Frisch, XBMPRII, a novel Xenopus type II receptor mediating BMP signaling in embryonic tissues. 1998, Pubmed , Xenbase
Fritz, Regulation of the mRNAs encoding proteins of the BMP signaling pathway during the maternal stages of Xenopus development. 2001, Pubmed , Xenbase
Fuerer, Nodal·Gdf1 heterodimers with bound prodomains enable serum-independent nodal signaling and endoderm differentiation. 2014, Pubmed
Fujiwara, Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse. 2002, Pubmed
Fujiwara, Bone morphogenetic protein 4 in the extraembryonic mesoderm is required for allantois development and the localization and survival of primordial germ cells in the mouse. 2001, Pubmed
Fukumoto, Serotonin signaling is a very early step in patterning of the left-right axis in chick and frog embryos. 2005, Pubmed , Xenbase
Furtado, BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4. 2008, Pubmed
Fürthauer, sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish. 2001, Pubmed
Fürthauer, Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling. 2002, Pubmed
Fürthauer, Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. 2004, Pubmed
Gage, Dosage requirement of Pitx2 for development of multiple organs. 1999, Pubmed
Gaio, A role of the cryptic gene in the correct establishment of the left-right axis. 1999, Pubmed
Galli, Glypican 4 modulates FGF signalling and regulates dorsoventral forebrain patterning in Xenopus embryos. 2003, Pubmed , Xenbase
Gamse, Early anteroposterior division of the presumptive neurectoderm in Xenopus. 2001, Pubmed , Xenbase
Garcia Abreu, Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems. 2002, Pubmed
Garric, Pitx2c ensures habenular asymmetry by restricting parapineal cell number. 2014, Pubmed
Gawantka, Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1. 1995, Pubmed , Xenbase
Geach, Molecular determinants of Xolloid action in vivo. 2008, Pubmed , Xenbase
Geng, Follistatin-like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development. 2011, Pubmed
Gerhart, Changing the axis changes the perspective. 2002, Pubmed , Xenbase
Gerhart, Inversion of the chordate body axis: are there alternatives? 2000, Pubmed
Gilardelli, Functional and hierarchical interactions among zebrafish vox/vent homeobox genes. 2004, Pubmed
Glavic, Xiro-1 controls mesoderm patterning by repressing bmp-4 expression in the Spemann organizer. 2001, Pubmed , Xenbase
Glinka, Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. 1998, Pubmed , Xenbase
Glister, Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: actions of BMP-4, -6 and -7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin. 2004, Pubmed
Glister, Comparison of bioactivities, binding properties and intrafollicular levels of bovine follistatins. 2015, Pubmed
Godsave, Clonal analysis of mesoderm induction in Xenopus laevis. 1989, Pubmed , Xenbase
Gómez-Skarmeta, The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4. 2001, Pubmed , Xenbase
Gönczy, Asymmetric cell division and axis formation in the embryo. 2005, Pubmed
Goodman, BMP1-related metalloproteinases promote the development of ventral mesoderm in early Xenopus embryos. 1998, Pubmed , Xenbase
Gore, The zebrafish dorsal axis is apparent at the four-cell stage. 2005, Pubmed
Gourronc, Nodal activity around Kupffer's vesicle depends on the T-box transcription factors Notail and Spadetail and on Notch signaling. 2007, Pubmed
Grande, Nodal signalling is involved in left-right asymmetry in snails. 2009, Pubmed
Granier, Nodal cis-regulatory elements reveal epiblast and primitive endoderm heterogeneity in the peri-implantation mouse embryo. 2011, Pubmed
Green, Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. 1992, Pubmed , Xenbase
Green, Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate. 1990, Pubmed , Xenbase
Gritsman, The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. 1999, Pubmed , Xenbase
Gritsman, Nodal signaling patterns the organizer. 2000, Pubmed , Xenbase
Groppe, Structural basis of BMP signaling inhibition by Noggin, a novel twelve-membered cystine knot protein. 2003, Pubmed
Groppe, Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. 2002, Pubmed
Groppe, Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4. 1998, Pubmed
Gros, Cell movements at Hensen's node establish left/right asymmetric gene expression in the chick. 2009, Pubmed , Xenbase
Gu, The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo. 1999, Pubmed
Gu, The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse. 1998, Pubmed
Gurdon, Direct and continuous assessment by cells of their position in a morphogen gradient. 1995, Pubmed
Gurdon, Activin signalling and response to a morphogen gradient. 1994, Pubmed , Xenbase
Guzman-Ayala, Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells. 2009, Pubmed
Guzman-Ayala, Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment. 2004, Pubmed
Hagos, Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish. 2007, Pubmed
Hamada, In search of Turing in vivo: understanding Nodal and Lefty behavior. 2012, Pubmed
Hammerschmidt, Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. 1996, Pubmed
Hammerschmidt, dino and mercedes, two genes regulating dorsal development in the zebrafish embryo. 1996, Pubmed
Han, αE-catenin-dependent mechanotransduction is essential for proper convergent extension in zebrafish. 2016, Pubmed
Hanel, Eye and neural defects associated with loss of GDF6. 2006, Pubmed , Xenbase
Hans, Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b. 2007, Pubmed
Hansson, A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells. 2009, Pubmed
Harms, Tomoregulin-1 (TMEFF1) inhibits nodal signaling through direct binding to the nodal coreceptor Cripto. 2003, Pubmed , Xenbase
Harvey, Visualisation and quantification of morphogen gradient formation in the zebrafish. 2009, Pubmed
Hashiguchi, Anteroposterior and dorsoventral patterning are coordinated by an identical patterning clock. 2013, Pubmed , Xenbase
Hashimoto, Translation of anterior-posterior polarity into left-right polarity in the mouse embryo. 2010, Pubmed
Hashimoto, The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish. 2004, Pubmed , Xenbase
Hashimoto, Zebrafish Dkk1 functions in forebrain specification and axial mesendoderm formation. 2000, Pubmed , Xenbase
Hashimoto-Partyka, Nodal signaling in Xenopus gastrulae is cell-autonomous and patterned by beta-catenin. 2003, Pubmed , Xenbase
Hata, OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. 2000, Pubmed , Xenbase
Hatayama, IP3 signaling is required for cilia formation and left-right body axis determination in Xenopus embryos. 2011, Pubmed , Xenbase
Hatta, The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. 1991, Pubmed
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