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XB-ART-10660
DNA Seq 2000 Jan 01;111-2:131-5. doi: 10.3109/10425170009033980.
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Isolation of rat mitochondrial transcription factor A (r-Tfam) cDNA.

Inagaki H , Hayashi T , Matsushima Y , Lin KH , Maeda S , Ichihara S , Kitagawa Y , Saito T .


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We have isolated rat mitochondrial transcription factor A (Tfam; formerly known as mtTFA) cDNA clones from a rat cerebellum cDNA library using human Tfam cDNA as a probe. The deduced amino acid sequence of r-Tfam shows 62% and 89% overall identity to human and mouse Tfam, respectively. We also show the presence of two r-Tfam isoforms in testis as for mouse. Our findings suggest that the mechanisms underlying transcription of mitochondrial genes are conserved among rat, mouse, and human.

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Species referenced: Xenopus
Genes referenced: tfam