XB-ART-1576
Dev Cell
2005 Aug 01;92:171-2. doi: 10.1016/j.devcel.2005.07.005.
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A small gem with great powers: geminin keeps neural progenitors thriving.
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Timing and extent of cell expansion and specialization in the developing nervous system are tightly controlled. In a recent issue of Genes and Development, Seo and coworkers (2005a) show that geminin (Gem), a protein involved in cell cycle control, also regulates the transition from proliferating neural progenitors to differentiating neurons.
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Species referenced: Xenopus
Genes referenced: cdt1 gem gmnn neurod1 six3