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XB-ART-20434
Gene 1994 Dec 15;1502:331-3.
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Identification and characterization of a cDNA encoding ribosomal protein S12 from Xenopus laevis.

Seery LT , Schoenberg DR , Canning ME , Whitehead AS .


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The complete nucleotide (nt) sequence of the cDNA clone XL-S12, encoding a Xenopus laevis (Xl) homologue of the mammalian ribosomal protein S12, has been determined. The sequence predicts a Xl S12 protein of 132 amino acids (aa) with a molecular mass of 14.7 kDa. Xl S12 shares 95 and 97% aa sequence identity with the human and murine S12 proteins, respectively. Analysis of nt substitution patterns and rates indicates that S12 is a very highly constrained protein, evolving at an estimated rate of only 0.03 x 10(-9) non-synonymous (protein-altering) substitutions per site per year.

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