XB-ART-2914
Gene Expr Patterns
2004 Oct 01;46:695-9. doi: 10.1016/j.modgep.2004.04.004.
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Identification of distinct genes with restricted expression in the somitic mesoderm in Xenopus embryo.
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We have used whole-mount in situ hybridisation to identify genes expressed in the somitic mesoderm during Xenopus early development. We report here the analysis of eight genes whose expression pattern has not been described previously. They include the Xenopus homologues of eukaryotic initiation factor 2beta, methionine adenosyltransferase II, serine dehydratase, alpha-adducin, oxoglutarate dehydrogenase, fragile X mental retardation syndrome related protein 1, monocarboxylate transporter and voltage-dependent anion channel 1. Interestingly, these genes exhibit very dynamic expression pattern during early development. At early gastrula stages several genes do not show localised expression pattern, while other genes are expressed in the marginal mesoderm or in ectoderm. As development proceeds, the expression of these genes is gradually restricted to different compartments of somite. This study thus reveals an unexpected dynamic expression pattern for various genes with distinct function in vertebrates.
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Species referenced: Xenopus
Genes referenced: add1 eif2b1 fxr1 mat2a myod1 ogdh sds slc16a1 vdac1
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