XB-ART-30447
Comp Biochem Physiol C Comp Pharmacol Toxicol
1983 Jan 01;742:311-7. doi: 10.1016/0742-8413(83)90106-8.
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Induction of metallothionein and effect on essential metals in cadmium-loaded frog Xenopus laevis.
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1. Cadmium (Cd) was administered orally as metallothionein (MT) in food or intramuscularly as MT and Cd2+ into a frog Xenopus laevis. 2. Oral administration resulted in low accumulation of Cd without affecting essential metal levels. 3. Intramuscular administrations of Cd as MT and Cd2+ resulted in accumulation of Cd in the kidney and in the liver and kidney, respectively, by inducing a Cd-binding protein which has properties characteristic of MT.
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