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XB-ART-30644
Proc Natl Acad Sci U S A 1982 Jun 01;7912:3789-93.
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Stimulation of Xenopus oocyte protein synthesis by microinjected adenovirus RNA.

Richter JD , Jones NC , Smith LD .


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The ability of injected heterologous mRNAs to compete with endogenous mRNAs in Xenopus oocytes was assayed. In confirmation of previous reports, globin mRNA translation in oocytes results in a concomitant decrease in endogenous protein synthesis. In contrast, injection of adenovirus 5 mRNA into the oocyte results in a stimulation of endogenous protein synthesis. The stimulation is dose dependent and does not require nuclear transcription in the oocyte. Preliminary mapping data suggest that the stimulatory RNA is a product of one of the viral immediate early genes.

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References [+] :
Allende, The degradation of ribonucleic acids injected into Xenopus laevis oocytes. 1974, Pubmed, Xenbase