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Cannata SM
,
Bernardini S
,
Filoni S
,
Gargioli C
.
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The outer cornea and pericorneal epidermis (lentogenic area) of larval Xenopus laevis are the only epidermal regions competent to regenerate a lens under the influence of the retinal inducer. However, the headepidermis of the lentogenic area can acquire the lens-regenerating competence following transplantation of an eye beneath it. In this paper we demonstrate that both the outer cornea and the headepidermis covering a transplanted eye are capable of responding not only to the retinal inducer of the larval eye but also to the inductive action of the embryonic optic vesicle by synthesizing crystallins. As the optic vesicle is a very weak lens inductor, which promotes crystallin synthesis only on the lens biased ectoderm of the embryo, these results indicate that the lens-forming competence in the outer cornea and epidermis of larval X. laevis corresponds to the persistence and acquisition of a condition similar to that of the embryonic biased ectoderm.
Arresta,
Lens-forming competence in the epidermis of Xenopus laevis during development.
2005, Pubmed,
Xenbase
Arresta,
Lens-forming competence in the epidermis of Xenopus laevis during development.
2005,
Pubmed
,
Xenbase
Bosco,
Eye factors and lens-forming transformations of outer cornea in Xenopus laevis larvae.
1986,
Pubmed
,
Xenbase
Bosco,
Lens formation from cornea in the presence of the old lens in larval Xenopus laevis.
1980,
Pubmed
,
Xenbase
Bosco,
Relationships between eye factors and lens-forming transformations in the cornea and pericorneal epidermis of larval Xenopus laevis.
1979,
Pubmed
,
Xenbase
Bosco,
In Vivo and in Vitro Experimental Analysis of Lens Regeneration in Larval Xenopus laevis: (lens/regeneration/transdifferentiation).
1993,
Pubmed
,
Xenbase
Bosco,
Relationships between Presence of the Eye Cup and Maintenance of Lens-Forming Capacity in Larval Xenopus laevis.
1992,
Pubmed
,
Xenbase
Cannata,
Tissue interactions and lens-forming competence in the outer cornea of larval Xenopus laevis.
2003,
Pubmed
,
Xenbase
Filoni,
The role of neural retina in lens regeneration from cornea in larval Xenopus laevis.
1982,
Pubmed
,
Xenbase
Filoni,
The inhibition of cell proliferation by mitomycin C does not prevent transdifferentiation of outer cornea into lens in larval Xenopus laevis.
1995,
Pubmed
,
Xenbase
Filoni,
Experimental analysis of lens-forming capacity in Xenopus borealis larvae.
2006,
Pubmed
,
Xenbase
FREEMAN,
LENS REGENERATION FROM THE CORNEA IN XENOPUS LAEVIS.
1963,
Pubmed
,
Xenbase
Gargioli,
The lens-regenerating competence in the outer cornea and epidermis of larval Xenopus laevis is related to pax6 expression.
2008,
Pubmed
,
Xenbase
Grainger,
Defining intermediate stages in cell determination: acquisition of a lens-forming bias in head ectoderm during lens determination.
1997,
Pubmed
,
Xenbase
Grainger,
Reinvestigation of the role of the optic vesicle in embryonic lens induction.
1988,
Pubmed
,
Xenbase
Grainger,
Embryonic lens induction: shedding light on vertebrate tissue determination.
1992,
Pubmed
,
Xenbase
Henry,
The matured eye of Xenopus laevis tadpoles produces factors that elicit a lens-forming response in embryonic ectoderm.
1995,
Pubmed
,
Xenbase
Henry,
Inductive interactions in the spatial and temporal restriction of lens-forming potential in embryonic ectoderm of Xenopus laevis.
1987,
Pubmed
,
Xenbase
Henry,
Early tissue interactions leading to embryonic lens formation in Xenopus laevis.
1990,
Pubmed
,
Xenbase
Khosrowshahian,
Lens and retina formation require expression of Pitx3 in Xenopus pre-lens ectoderm.
2005,
Pubmed
,
Xenbase
Ogino,
Sequential activation of transcription factors in lens induction.
2000,
Pubmed
,
Xenbase
Reeve,
Lens regeneration from cornea of larval Xenopus laevis in the presence of the lens.
1978,
Pubmed
,
Xenbase
Saha,
Embryonic lens induction: more than meets the optic vesicle.
1989,
Pubmed
,
Xenbase
Servetnick,
Changes in neural and lens competence in Xenopus ectoderm: evidence for an autonomous developmental timer.
1991,
Pubmed
,
Xenbase
Zygar,
Gene activation during early stages of lens induction in Xenopus.
1998,
Pubmed
,
Xenbase
