Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
Species of frogs that develop directly have removed the tadpole from their ontogeny and form adult structures precociously. To see whether cell cycle regulators could be involved in this altered embryogenesis, we examined the expression of ccnd1, ccnd2, and mycn in embryos of the direct developing frog, Eleutherodactylus coqui. Notable differences compared to embryos of Xenopus laevis, a species with a tadpole, included prominent expression of ccnd2 in the midbrain and ccnd1 in the mandibular neural crest. The former may contribute to the precocious appearance of the adult-type visual system and the latter to the adult-type jaw. Large domains of ccnd2 and mycn presage the early appearance of limb buds, and ccnd1 and mycn are implicated in digit development.
Abu-Daya,
The secreted integrin ligand nephronectin is necessary for forelimb formation in Xenopus tropicalis.
2011, Pubmed,
Xenbase
Abu-Daya,
The secreted integrin ligand nephronectin is necessary for forelimb formation in Xenopus tropicalis.
2011,
Pubmed
,
Xenbase
Beckham,
Localization of RNAs in oocytes of Eleutherodactylus coqui, a direct developing frog, differs from Xenopus laevis.
2003,
Pubmed
,
Xenbase
Bellmeyer,
The protooncogene c-myc is an essential regulator of neural crest formation in xenopus.
2003,
Pubmed
,
Xenbase
Brown,
Thyroid hormone controls multiple independent programs required for limb development in Xenopus laevis metamorphosis.
2005,
Pubmed
,
Xenbase
Callery,
Thyroid hormone-dependent metamorphosis in a direct developing frog.
2000,
Pubmed
,
Xenbase
Callery,
Frogs without polliwogs: evolution of anuran direct development.
2001,
Pubmed
,
Xenbase
Cameron,
The absence of cell death during development of free digits in amphibians.
1977,
Pubmed
,
Xenbase
Elinson,
Secondary coverage of the yolk by the body wall in the direct developing frog, Eleutherodactylus coqui: an unusual process for amphibian embryos.
1998,
Pubmed
,
Xenbase
Elinson,
Developmental diversity of amphibians.
2012,
Pubmed
,
Xenbase
Elinson,
Raldh expression in embryos of the direct developing frog Eleutherodactylus coqui and the conserved retinoic acid requirement for forelimb initiation.
2008,
Pubmed
,
Xenbase
Elinson,
Direct development: an alternative way to make a frog.
2001,
Pubmed
Elinson,
Metamorphosis in a frog that does not have a tadpole.
2013,
Pubmed
,
Xenbase
Endo,
Shh expression in developing and regenerating limb buds of Xenopus laevis.
1997,
Pubmed
,
Xenbase
Fang,
Patterns of distal-less gene expression and inductive interactions in the head of the direct developing frog Eleutherodactylus coqui.
1996,
Pubmed
,
Xenbase
Franssen,
Limb chondrogenesis of the seepage salamander, Desmognathus aeneus (amphibia: plethodontidae).
2005,
Pubmed
Hanken,
Cranial ontogeny in the direct-developing frog, Eleutherodactylus coqui (Anura: Leptodactylidae), analyzed using whole-mount immunohistochemistry.
1992,
Pubmed
Hanken,
Evolution of cranial development and the role of neural crest: insights from amphibians.
2005,
Pubmed
Hanken,
Limb development in a "nonmodel" vertebrate, the direct-developing frog Eleutherodactylus coqui.
2001,
Pubmed
,
Xenbase
Jennings,
Mechanistic basis of life history evolution in anuran amphibians: thyroid gland development in the direct-developing frog, Eleutherodactylus coqui.
1998,
Pubmed
Kato,
Tissue Distribution of N-myc Expression in the Early Organogenesis Period of the Mouse Embryo: (N-myc/mouse embryo/in situ hybridization/neural/crest/sclerotome).
1991,
Pubmed
Kerney,
Early cranial patterning in the direct-developing frog Eleutherodactylus coqui revealed through gene expression.
2010,
Pubmed
,
Xenbase
Kerney,
Gene expression reveals unique skeletal patterning in the limb of the direct-developing frog, Eleutherodactylus coqui.
2008,
Pubmed
,
Xenbase
Martin,
A novel role for lbx1 in Xenopus hypaxial myogenesis.
2006,
Pubmed
,
Xenbase
Montero,
Sculpturing digit shape by cell death.
2010,
Pubmed
Muntz,
Myogenesis in the trunk and leg during development of the tadpole of Xenopus laevis (Daudin 1802).
1975,
Pubmed
,
Xenbase
Nath,
Expression of a cardiac myosin gene in non-heart tissues of developing frogs.
2013,
Pubmed
,
Xenbase
Olsson,
Cranial neural crest-cell migration in the direct-developing frog, Eleutherodactylus coqui: molecular heterogeneity within and among migratory streams.
2002,
Pubmed
Ota,
Activities of N-Myc in the developing limb link control of skeletal size with digit separation.
2007,
Pubmed
Sabo,
Lbx1 expression and frog limb development.
2009,
Pubmed
,
Xenbase
Satoh,
Characteristics of initiation and early events for muscle development in the Xenopus limb bud.
2005,
Pubmed
,
Xenbase
Sawai,
Organization and expression of the chicken N-myc gene.
1990,
Pubmed
Schlosser,
Mosaic evolution of neural development in anurans: acceleration of spinal cord development in the direct developing frog Eleutherodactylus coqui.
2003,
Pubmed
,
Xenbase
Schlosser,
Development of the retina is altered in the directly developing frog Eleutherodactylus coqui (Leptodactylidae).
1997,
Pubmed
,
Xenbase
Schlosser,
Development of the retinotectal system in the direct-developing frog Eleutherodactylus coqui in comparison with other anurans.
2008,
Pubmed
,
Xenbase
Singamsetty,
Novel regulation of yolk utilization by thyroid hormone in embryos of the direct developing frog Eleutherodactylus coqui.
2010,
Pubmed
,
Xenbase
Tarin,
Early limb development of Xenopus laevis.
1971,
Pubmed
,
Xenbase
Towers,
Integration of growth and specification in chick wing digit-patterning.
2008,
Pubmed
Vernon,
The developmental expression of cell cycle regulators in Xenopus laevis.
2003,
Pubmed
,
Xenbase
Vize,
Expression of the N-myc proto-oncogene during the early development of Xenopus laevis.
1990,
Pubmed
,
Xenbase
Vlaskalin,
Growth and apoptosis during larval forelimb development and adult forelimb regeneration in the newt ( Notophthalmus viridescens).
2004,
Pubmed
Welten,
3D expression patterns of cell cycle genes in the developing chick wing and comparison with expression patterns of genes implicated in digit specification.
2011,
Pubmed
Zuzarte-Luis,
Programmed cell death in the embryonic vertebrate limb.
2005,
Pubmed
