XB-ART-47999
Curr Biol
2013 Aug 05;2315:R652-4. doi: 10.1016/j.cub.2013.06.055.
Show Gene links
Show Anatomy links
Development: scaling to size by protease inhibition.
???displayArticle.abstract???
The dorsal half of bisected Xenopus laevis embryos can regenerate a well-proportioned organism on a smaller scale. A new study indicates that the removal of ventral tissue generates a steeper Chordin gradient by reducing Sizzled, a secreted inhibitor of Tolloid chordinases.
???displayArticle.pubmedLink??? 23928082
???displayArticle.link??? Curr Biol
???displayArticle.grants???
Species referenced: Xenopus laevis
Genes referenced: bmp1 chrd frzb2 szl
???displayArticle.morpholinos??? chrd.1 MO1 chrd.1 MO2 szl MO1
???attribute.lit??? ???displayArticles.show???
|
|
References :
Inomata,
Scaling of dorsal-ventral patterning by embryo size-dependent degradation of Spemann's organizer signals.
2013, Pubmed,
Xenbase