XB-ART-4850
Dev Cell
2003 Aug 01;52:187-8. doi: 10.1016/s1534-5807(03)00230-2.
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The quest for the holy "G" of chromosomal passengers.
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Twelve years after reporting a novel chromosomal passenger protein, Mollinari et al. in this issue of Developmental Cell finally report its molecular identification, and the results are stunning. TD-60 is a member of the RCC1 family of guanine nucleotide exchange factors implicating small GTPases in chromosome congression and cytokinesis.
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Species referenced: Xenopus
Genes referenced: aurka aurkb incenp kpna1 kpnb1 rac1 ran rcc1 tbx2 tpx2
References :
Mollinari,
The mammalian passenger protein TD-60 is an RCC1 family member with an essential role in prometaphase to metaphase progression.
2003, Pubmed