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Lab Chip
2013 Nov 07;1321:4160-3. doi: 10.1039/c3lc50571e.
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A novel approach to quantifying ciliary physiology: microfluidic mixing driven by a ciliated biological surface.
Jonas S
,
Zhou E
,
Deniz E
,
Huang B
,
Chandrasekera K
,
Bhattacharya D
,
Wu Y
,
Fan R
,
Deserno TM
,
Khokha MK
,
Choma MA
.
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From the lungs to the central nervous system, cilia-driven fluid flow plays a fundamental role in many facets of life. Yet, there are few quantitative methods for analysing the function of ciliated surfaces. Here, we report a novel microfluidic approach for quantifying the performance of a ciliated surface using mixing performance as an integrated readout.
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