Bandín S , Morona R , González A .

	FIGURE 1 | Expression of early markers of the diencephalic prepatterning and formation of the Zli. Microphotographs of lateral views of the forebrain in whole mounts labeled for double in situ hybridization (ISH) to reveal Shh (purple) and Gbx2 (orange) at the embryonic stages indicated (A–D); the orientation is indicated in each panel to highlight the dorsoventral and rostrocaudal change of the axis through the thalamus at each stage. (E–O): Microphotographs of whole mounts (I,J,M) and sagittal (E,F,H,K,L,N) or transverse (G,O) sections of embryos at stages 33/34. The photographs correspond to single ISH (E,I,J), single immunohistochemistry (IHC; K), and combinations of double ISH (F,G,M–O) or combined ISH and IHC (H,L). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. The levels of the transverse sections (G,O) are indicated in photographs (F,N), respectively. Scale bars = 100 µm (E,F,L–N), 50 µm (A–D,G–K,O). See list for abbreviations.
	FIGURE 2 | Expression of thalamic markers at early embryonic stages 37/38. Microphotographs of whole mounts (A,N) and sagittal (B,C,E,J,L,O,R) or transverse (D,F–I,K,M,P,Q) sections of embryos at stages 37/38. Photographs correspond to single ISH (purple; A,I), double ISH (purple/orange; G,N–Q) and combination of ISH (purple) with IHC (brown) (B–E, F,H,J,K,L,M,R). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. At these stage c-Th and r-Th subdivision of the thalamus were distinguished (M). The levels of the transverse sections (D,F,P) are indicated in photographs (C,E,O), respectively. Scale bars = 100 µm (A,B,L,N,O), 50 µm (C–K,M,P–R). See list for abbreviations.
	FIGURE 3 | Expression of thalamic markers at embryonic stages 40/41. Microphotographs of transverse (A,B,C,E,F,H,J,L,M) or sagittal (D,G,I,K) sections of embryos at stages 40/41. Photographs correspond to single ISH (purple; A,B), single IHC (C) double ISH (purple/orange; D,E,G,H,K) and combination of ISH (purple) with IHC (brown) (F,I,J,L,M). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. Note the mutually exclusive expression between Gbx2 in the thalamus and the Xiro1 in the habenular region, (compare E and H; D and G). The levels of the transverse sections (H,J) are indicated in photographs (G,I), respectively. Scale bars = 100 µm (G,K), 50 µm (A–F,H,I,K–M). See list for abbreviations.
	FIGURE 4 Expression of thalamic markers at embryonic stages 40/41. Microphotographs of transverse (A–E,G–I,K–M) or sagittal (F,J,N,O) sections of embryos at stages 40/41. In all cases, photographs correspond to combination of ISH (purple) with IHC (brown), except for a double fluorescent ISH (red) and IHC (green) panel (E) and two single ISH (purple; H,I). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. The levels of the transverse sections (A,K,L) are indicated in photograph (J), the level of (G) is indicated in (F), and the level of (M) is indicated in (N). Scale bars = 50 µm. See list for abbreviations.
	FIGURE 5 | Expression of thalamic markers at embryonic stage 45. Microphotographs of sagittal (A,E,G–I,K,O,R,T), transverse (B,F,J,L–N,P,Q,S,U), and horizontal (C,D) sections of embryos at stage 45. In all cases, photographs correspond to combination of ISH (purple) with IHC (brown), except for the double fluorescent ISH (red) and IHC (green) panels (K–O) and a double fluorescent IHC (P). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections; in the horizontal sections rostral is to the left. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. The levels of the transverse section (B) is indicated in photograph (A), and the levels of (L,M) are indicated in (K). Scale bars = 100 µm (K–M,O), 50 µm (A–J,N,P–U). See list for abbreviations.
	FIGURE 6 | Main markers involved in the early thalamic prepatterning. Schemes of lateral views of the forebrain at early and late embryonic stages representing the main expressed factors that lead in Xenopus to a first induction of the thalamic region and the position of the Zli (A), and the subsequent prepatterning of the thalamus and formation of the Zli (B). The prethalamo-thalamic boundary (PTB) can be inferred in the zone where the rostral and caudal expressions abut.
	FIGURE 7 | Expression patterns of the main thalamic markers. Summary diagrams representing in lateral view of the forebrain the extent of the expressions of the main markers analyzed in Xenopus with respect to the thalamus and neighboring regions at early (A,B) and late (C,D) embryonic stages.
	lhx9 (LIM homeobox 9) gene expression in Xenopus laevis embryonic brain, NF stage 40/41, transverse section, dorsal up,
	lhx2 (LIM homeobox 2) gene expression in Xenopus laevis embryonic brain, NF stage 40/41, transverse section, dorsal up,
	nkx2-2
	dll4/isl1 abs
	Figure 1. Expression of early markers of the diencephalic prepatterning and formation of the Zli. Microphotographs of lateral views of the forebrain in whole mounts labeled for double in situ hybridization (ISH) to reveal Shh (purple) and Gbx2 (orange) at the embryonic stages indicated (A–D); the orientation is indicated in each panel to highlight the dorsoventral and rostrocaudal change of the axis through the thalamus at each stage. (E–O): Microphotographs of whole mounts (I,J,M) and sagittal (E,F,H,K,L,N) or transverse (G,O) sections of embryos at stages 33/34. The photographs correspond to single ISH (E,I,J), single immunohistochemistry (IHC; K), and combinations of double ISH (F,G,M–O) or combined ISH and IHC (H,L). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. The levels of the transverse sections (G,O) are indicated in photographs (F,N), respectively. Scale bars = 100 μm (E,F,L–N), 50 μm (A–D,G–K,O). See list for abbreviations.
	Figure 2. Expression of thalamic markers at early embryonic stages 37/38. Microphotographs of whole mounts (A,N) and sagittal (B,C,E,J,L,O,R) or transverse (D,F–I,K,M,P,Q) sections of embryos at stages 37/38. Photographs correspond to single ISH (purple; A,I), double ISH (purple/orange; G,N–Q) and combination of ISH (purple) with IHC (brown) (B–E, F,H,J,K,L,M,R). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. At these stage c-Th and r-Th subdivision of the thalamus were distinguished (M). The levels of the transverse sections (D,F,P) are indicated in photographs (C,E,O), respectively. Scale bars = 100 μm (A,B,L,N,O), 50 μm (C–K,M,P–R). See list for abbreviations.
	Figure 3. Expression of thalamic markers at embryonic stages 40/41. Microphotographs of transverse (A,B,C,E,F,H,J,L,M) or sagittal (D,G,I,K) sections of embryos at stages 40/41. Photographs correspond to single ISH (purple; A,B), single IHC (C) double ISH (purple/orange; D,E,G,H,K) and combination of ISH (purple) with IHC (brown) (F,I,J,L,M). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. Note the mutually exclusive expression between Gbx2 in the thalamus and the Xiro1 in the habenular region, (compare E and H; D and G). The levels of the transverse sections (H,J) are indicated in photographs (G,I), respectively. Scale bars = 100 μm (G,K), 50 μm (A–F,H,I,K–M). See list for abbreviations.
	Figure 4. Expression of thalamic markers at embryonic stages 40/41. Microphotographs of transverse (A–E,G–I,K–M) or sagittal (F,J,N,O) sections of embryos at stages 40/41. In all cases, photographs correspond to combination of ISH (purple) with IHC (brown), except for a double fluorescent ISH (red) and IHC (green) panel (E) and two single ISH (purple; H,I). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. The levels of the transverse sections (A,K,L) are indicated in photograph (J), the level of (G) is indicated in (F), and the level of (M) is indicated in (N). Scale bars = 50 μm. See list for abbreviations.
	Figure 5. Expression of thalamic markers at embryonic stage 45. Microphotographs of sagittal (A,E,G–I,K,O,R,T), transverse (B,F,J,L–N,P,Q,S,U), and horizontal (C,D) sections of embryos at stage 45. In all cases, photographs correspond to combination of ISH (purple) with IHC (brown), except for the double fluorescent ISH (red) and IHC (green) panels (K–O) and a double fluorescent IHC (P). The markers labeled are indicated in the upper left of each photograph. All images are oriented following the same standard: dorsal is upwards in transverse and sagittal sections, and rostral is to the left in sagittal sections; in the horizontal sections rostral is to the left. The neuromeric boundaries and main brain subdivisions are indicated to assist in the precise localization of the labeling. The levels of the transverse section (B) is indicated in photograph (A), and the levels of (L,M) are indicated in (K). Scale bars = 100 μm (K–M,O), 50 μm (A–J,N,P–U). See list for abbreviations.
	Figure 6. Main markers involved in the early thalamic prepatterning. Schemes of lateral views of the forebrain at early and late embryonic stages representing the main expressed factors that lead in Xenopus to a first induction of the thalamic region and the position of the Zli (A), and the subsequent prepatterning of the thalamus and formation of the Zli (B). The prethalamo-thalamic boundary (PTB) can be inferred in the zone where the rostral and caudal expressions abut.
	Figure 7. Expression patterns of the main thalamic markers. Summary diagrams representing in lateral view of the forebrain the extent of the expressions of the main markers analyzed in Xenopus with respect to the thalamus and neighboring regions at early (A,B) and late (C,D) embryonic stages.
	Figure 8. Diagram of the main expression patterns for markers of the thalamic subdivisions. Schematic representation of the early progenitor domains in the thalamus of Xenopus, indicating the main markers found in each domain in the present study. (A) is a drawing of a lateral view of the thalamus in which a color-code for the distinct expression patterns for the markers used is depicted in (B). (C) corresponds to the representation of a transverse section at the level indicated in (A) in which the extent of the thalamic progenitor domains is indicated in relation to the Zli.

Abbasi, Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development. 2010, Pubmed

Abbasi, Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development. 2010, Pubmed
Arce, Diversity of LEF/TCF action in development and disease. 2006, Pubmed
Archbold, How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway. 2012, Pubmed
Bachy, The LIM-homeodomain gene family in the developing Xenopus brain: conservation and divergences with the mouse related to the evolution of the forebrain. 2001, Pubmed , Xenbase
Bachy, GABAergic specification in the basal forebrain is controlled by the LIM-hd factor Lhx7. 2006, Pubmed , Xenbase
Bachy, Defining pallial and subpallial divisions in the developing Xenopus forebrain. 2002, Pubmed , Xenbase
Bandín, Immunohistochemical analysis of Pax6 and Pax7 expression in the CNS of adult Xenopus laevis. 2014, Pubmed , Xenbase
Bandín, Regional expression of Pax7 in the brain of Xenopus laevis during embryonic and larval development. 2013, Pubmed , Xenbase
Barth, Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. 1995, Pubmed
Bell, Dynamic domains of gene expression in the early avian forebrain. 2001, Pubmed
Bluske, β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus. 2012, Pubmed
Bluske, Differential activity of Wnt/beta-catenin signaling in the embryonic mouse thalamus. 2009, Pubmed
Braun, Wnt signaling is required at distinct stages of development for the induction of the posterior forebrain. 2003, Pubmed
Briscoe, Making a grade: Sonic Hedgehog signalling and the control of neural cell fate. 2009, Pubmed
Brox, Expression of the genes GAD67 and Distal-less-4 in the forebrain of Xenopus laevis confirms a common pattern in tetrapods. 2003, Pubmed , Xenbase
Brox, Expression of the genes Emx1, Tbr1, and Eomes (Tbr2) in the telencephalon of Xenopus laevis confirms the existence of a ventral pallial division in all tetrapods. 2004, Pubmed , Xenbase
Bulfone, Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. 1993, Pubmed
Caballero, Cell-autonomous repression of Shh by transcription factor Pax6 regulates diencephalic patterning by controlling the central diencephalic organizer. 2014, Pubmed
Cai, Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010, Pubmed
Chatterjee, Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates. 2014, Pubmed
Chatterjee, Patterning and compartment formation in the diencephalon. 2012, Pubmed
Chatterjee, Gbx2 regulates thalamocortical axon guidance by modifying the LIM and Robo codes. 2012, Pubmed
Chen, Transcription factor Gbx2 acts cell-nonautonomously to regulate the formation of lineage-restriction boundaries of the thalamus. 2009, Pubmed
Cho, TCF-4 binds beta-catenin and is expressed in distinct regions of the embryonic brain and limbs. 1998, Pubmed , Xenbase
Crick, A framework for consciousness. 2003, Pubmed
Domínguez, Characterization of the hypothalamus of Xenopus laevis during development. II. The basal regions. 2014, Pubmed , Xenbase
Domínguez, Characterization of the hypothalamus of Xenopus laevis during development. I. The alar regions. 2013, Pubmed , Xenbase
Domínguez, Sonic hedgehog expression during Xenopus laevis forebrain development. 2010, Pubmed , Xenbase
Domínguez, Ontogenetic distribution of the transcription factor nkx2.2 in the developing forebrain of Xenopus laevis. 2011, Pubmed , Xenbase
Echevarría, Neuroepithelial secondary organizers and cell fate specification in the developing brain. 2003, Pubmed
Epstein, Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms. 1999, Pubmed
Epstein, Regulation of thalamic development by sonic hedgehog. 2012, Pubmed
Ferran, Early pretectal gene expression pattern shows a conserved anteroposterior tripartition in mouse and chicken. 2008, Pubmed
Ferran, A model of early molecular regionalization in the chicken embryonic pretectum. 2007, Pubmed
Ferran, Genoarchitectonic profile of developing nuclear groups in the chicken pretectum. 2009, Pubmed
Figdor, Segmental organization of embryonic diencephalon. 1993, Pubmed
Garcia-Lopez, Fate map of the diencephalon and the zona limitans at the 10-somites stage in chick embryos. 2004, Pubmed
Garda, Expression patterns of Wnt8b and Wnt7b in the chicken embryonic brain suggest a correlation with forebrain patterning centers and morphogenesis. 2002, Pubmed
Gómez-Skarmeta, Xiro, a Xenopus homolog of the Drosophila Iroquois complex genes, controls development at the neural plate. 1998, Pubmed , Xenbase
Gómez-Skarmeta, Half a century of neural prepatterning: the story of a few bristles and many genes. 2003, Pubmed
González, An immunohistochemical approach to lungfish telencephalic organization. 2009, Pubmed
Grindley, Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon. 1997, Pubmed
Guinazu, Tissue interactions in the developing chick diencephalon. 2007, Pubmed
Haddad-Tóvolli, Mouse thalamic differentiation: gli-dependent pattern and gli-independent prepattern. 2012, Pubmed
Hagemann, The Tale of the Three Brothers - Shh, Wnt, and Fgf during Development of the Thalamus. 2012, Pubmed
Hashimoto, Expression of the zinc finger gene fez-like in zebrafish forebrain. 2000, Pubmed , Xenbase
Hashimoto-Torii, Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus. 2003, Pubmed
Hevner, Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other. 2002, Pubmed
Hirata, Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions. 2006, Pubmed
Hollyday, Wnt expression patterns in chick embryo nervous system. 1995, Pubmed
Houart, Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. 2002, Pubmed
Itoh, A role for iro1 and iro7 in the establishment of an anteroposterior compartment of the ectoderm adjacent to the midbrain-hindbrain boundary. 2002, Pubmed
Jeong, Patterning the zebrafish diencephalon by the conserved zinc-finger protein Fezl. 2007, Pubmed
Jeong, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. 2011, Pubmed
Jones, Expression of regulatory genes during differentiation of thalamic nuclei in mouse and monkey. 2004, Pubmed
Joven, Expression patterns of Pax6 and Pax7 in the adult brain of a urodele amphibian, Pleurodeles waltl. 2013, Pubmed
Joven, Spatiotemporal patterns of Pax3, Pax6, and Pax7 expression in the developing brain of a urodele amphibian, Pleurodeles waltl. 2013, Pubmed
Karlstrom, Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. 2003, Pubmed , Xenbase
Kataoka, Fgf8 controls regional identity in the developing thalamus. 2008, Pubmed
Kiecker, Hedgehog signaling from the ZLI regulates diencephalic regional identity. 2004, Pubmed
Kiecker, Compartments and their boundaries in vertebrate brain development. 2005, Pubmed
Kiecker, A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus. 2001, Pubmed , Xenbase
Kobayashi, Early subdivisions in the neural plate define distinct competence for inductive signals. 2002, Pubmed
Koenig, En2, Pax2/5 and Tcf-4 transcription factors cooperate in patterning the Xenopus brain. 2010, Pubmed , Xenbase
Korinek, Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse. 1998, Pubmed
Laberge, Thalamo-telencephalic pathways in the fire-bellied toad Bombina orientalis. 2008, Pubmed
Lagutin, Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development. 2003, Pubmed
Larsen, Boundary formation and compartition in the avian diencephalon. 2001, Pubmed
Lecaudey, Expression of the zebrafish Iroquois genes during early nervous system formation and patterning. 2005, Pubmed
Lee, Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. 1997, Pubmed , Xenbase
Lim, Patterning the developing diencephalon. 2007, Pubmed
Manuel, Role of Pax6 in forebrain regionalization. 2005, Pubmed
Marín, Basal ganglia organization in amphibians: evidence for a common pattern in tetrapods. 1998, Pubmed
Marín, A long, remarkable journey: tangential migration in the telencephalon. 2001, Pubmed
Martínez, Neurogenetic compartments of the mouse diencephalon and some characteristic gene expression patterns. 2000, Pubmed
Martínez, The isthmic organizer and brain regionalization. 2001, Pubmed
Martínez-de-la-Torre, Gbx2 expression in the late embryonic chick dorsal thalamus. , Pubmed
Martinez-Ferre, Molecular regionalization of the diencephalon. 2012, Pubmed
Matsuo-Takasaki, Cloning and expression of a novel zinc finger gene, Fez, transcribed in the forebrain of Xenopus and mouse embryos. 2000, Pubmed , Xenbase
McGinnis, Homeobox genes and axial patterning. 1992, Pubmed
Merzdorf, The zic1 gene is an activator of Wnt signaling. 2006, Pubmed , Xenbase
Moreno, Characterization of the bed nucleus of the stria terminalis in the forebrain of anuran amphibians. 2012, Pubmed , Xenbase
Moreno, Spatio-temporal expression of Pax6 in Xenopus forebrain. 2008, Pubmed , Xenbase
Moreno, Subdivisions of the turtle Pseudemys scripta hypothalamus based on the expression of regulatory genes and neuronal markers. 2012, Pubmed
Moreno, Islet1 as a marker of subdivisions and cell types in the developing forebrain of Xenopus. 2008, Pubmed , Xenbase
Moreno, Regionalization of the telencephalon in urodele amphibians and its bearing on the identification of the amygdaloid complex. 2007, Pubmed
Moreno, LIM-homeodomain genes as developmental and adult genetic markers of Xenopus forebrain functional subdivisions. 2004, Pubmed , Xenbase
Morona, Calbindin-D28k and calretinin expression in the forebrain of anuran and urodele amphibians: further support for newly identified subdivisions. 2008, Pubmed , Xenbase
Morona, Embryonic genoarchitecture of the pretectum in Xenopus laevis: a conserved pattern in tetrapods. 2011, Pubmed , Xenbase
Mueller, What is the Thalamus in Zebrafish? 2012, Pubmed
Mullor, Wnt signals are targets and mediators of Gli function. 2001, Pubmed
Nakagawa, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. 2001, Pubmed
Neary, Nuclear organization of the bullfrog diencephalon. 1983, Pubmed
Nieber, Comparative expression analysis of the neurogenins in Xenopus tropicalis and Xenopus laevis. 2009, Pubmed , Xenbase
Niehrs, Head in the WNT: the molecular nature of Spemann's head organizer. 1999, Pubmed
Oosterwegel, Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis. 1993, Pubmed
Osorio, Organisation of the lamprey (Lampetra fluviatilis) embryonic brain: insights from LIM-homeodomain, Pax and hedgehog genes. 2005, Pubmed
Parr, Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. 1993, Pubmed
Persson, Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. 2002, Pubmed , Xenbase
Peukert, Lhx2 and Lhx9 determine neuronal differentiation and compartition in the caudal forebrain by regulating Wnt signaling. 2011, Pubmed
Pratt, A role for Pax6 in the normal development of dorsal thalamus and its cortical connections. 2000, Pubmed
Price, A mouse gene related to Distal-less shows a restricted expression in the developing forebrain. 1991, Pubmed
Puelles, Brain segmentation and forebrain development in amniotes. 2001, Pubmed
Puelles, A segmental map of architectonic subdivisions in the diencephalon of the frog Rana perezi: acetylcholinesterase-histochemical observations. 1996, Pubmed
Puelles, A segmental morphological paradigm for understanding vertebrate forebrains. 1995, Pubmed
Puelles, Forebrain gene expression domains and the evolving prosomeric model. 2003, Pubmed
Puelles, Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization. 1993, Pubmed
Rétaux, Lhx9: a novel LIM-homeodomain gene expressed in the developing forebrain. 1999, Pubmed
Robertshaw, Irx3 and Pax6 establish differential competence for Shh-mediated induction of GABAergic and glutamatergic neurons of the thalamus. 2013, Pubmed
Rodríguez-Seguel, The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx. 2009, Pubmed , Xenbase
Rubenstein, The embryonic vertebrate forebrain: the prosomeric model. 1994, Pubmed
Ruiz i Altaba, Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog. 1998, Pubmed , Xenbase
Ruiz i Altaba, The emergent design of the neural tube: prepattern, SHH morphogen and GLI code. 2003, Pubmed
Sánchez-Arrones, Incipient forebrain boundaries traced by differential gene expression and fate mapping in the chick neural plate. 2009, Pubmed
Schimmang, Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt). 1992, Pubmed
Scholpp, Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon. 2006, Pubmed
Scholpp, Building a bridal chamber: development of the thalamus. 2010, Pubmed
Scholpp, Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon. 2007, Pubmed
Shimamura, Longitudinal organization of the anterior neural plate and neural tube. 1995, Pubmed
Stoykova, Forebrain patterning defects in Small eye mutant mice. 1996, Pubmed
Suzuki-Hirano, Dynamic spatiotemporal gene expression in embryonic mouse thalamus. 2011, Pubmed
Szabó, The role of Sonic hedgehog of neural origin in thalamic differentiation in the mouse. 2009, Pubmed
Tay, The development of the diencephalon in Xenopus. An autoradiographic study. 1982, Pubmed , Xenbase
Vieira, Sonic hedgehog from the basal plate and the zona limitans intrathalamica exhibits differential activity on diencephalic molecular regionalization and nuclear structure. 2006, Pubmed
Vieira, Thalamic development induced by Shh in the chick embryo. 2005, Pubmed
Vue, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. 2009, Pubmed
Vue, Characterization of progenitor domains in the developing mouse thalamus. 2007, Pubmed
Warren, Roles of Pax-6 in murine diencephalic development. 1997, Pubmed
Wilson, Early steps in the development of the forebrain. 2004, Pubmed
Yamazaki, The Lhx9 homeobox gene controls pineal gland development and prevents postnatal hydrocephalus. 2015, Pubmed
Zeltser, Shh-dependent formation of the ZLI is opposed by signals from the dorsal diencephalon. 2005, Pubmed
Zeng, Neurogenic development of the auditory areas of the midbrain and diencephalon in the Xenopus laevis and evolutionary implications. 2008, Pubmed , Xenbase
Zhang, Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development. 2014, Pubmed , Xenbase