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Ariey,
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.
2014, Pubmed
Ariey,
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.
2014,
Pubmed
Arnou,
The Plasmodium falciparum Ca(2+)-ATPase PfATP6: insensitive to artemisinin, but a potential drug target.
2011,
Pubmed
Cardi,
Purified E255L mutant SERCA1a and purified PfATP6 are sensitive to SERCA-type inhibitors but insensitive to artemisinins.
2010,
Pubmed
,
Xenbase
Chilongola,
Occurrence of pfatpase6 Single Nucleotide Polymorphisms Associated with Artemisinin Resistance among Field Isolates of Plasmodium falciparum in North-Eastern Tanzania.
2015,
Pubmed
David-Bosne,
Antimalarial screening via large-scale purification of Plasmodium falciparum Ca2+-ATPase 6 and in vitro studies.
2013,
Pubmed
David-Bosne,
Erratum: Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes.
2016,
Pubmed
,
Xenbase
Dogovski,
Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance.
2015,
Pubmed
Eckstein-Ludwig,
Artemisinins target the SERCA of Plasmodium falciparum.
2003,
Pubmed
,
Xenbase
Ghorbal,
Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system.
2014,
Pubmed
Jambou,
Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity.
2010,
Pubmed
Krishna,
Pumped up: reflections on PfATP6 as the target for artemisinins.
2014,
Pubmed
,
Xenbase
Krishna,
Artemisinins and the biological basis for the PfATP6/SERCA hypothesis.
2010,
Pubmed
Krishna,
Expression and functional characterization of a Plasmodium falciparum Ca2+-ATPase (PfATP4) belonging to a subclass unique to apicomplexan organisms.
2001,
Pubmed
,
Xenbase
Mbengue,
A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria.
2015,
Pubmed
Miotto,
Genetic architecture of artemisinin-resistant Plasmodium falciparum.
2015,
Pubmed
Mok,
Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.
2015,
Pubmed
Phompradit,
Molecular analysis of pfatp6 and pfmdr1 polymorphisms and their association with in vitro sensitivity in Plasmodium falciparum isolates from the Thai-Myanmar border.
2011,
Pubmed
Rottmann,
Spiroindolones, a potent compound class for the treatment of malaria.
2010,
Pubmed
Spillman,
Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials.
2013,
Pubmed
Straimer,
Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates.
2015,
Pubmed
Tun,
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker.
2015,
Pubmed
Uhlemann,
A single amino acid residue can determine the sensitivity of SERCAs to artemisinins.
2005,
Pubmed
,
Xenbase
Valderramos,
Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance.
2010,
Pubmed
,
Xenbase
