Chowdhury D , Turner M , Patriarchi T , Hergarden AC , Anderson D , Zhang Y , Sun J , Chen CY , Ames JB , Hell JW .

R01 AG055357 NIA NIH HHS , R01 EY012347 NEI NIH HHS , R01 MH097887 NIMH NIH HHS, R01 NS078792 NINDS NIH HHS

Araya, Activity-dependent dendritic spine neck changes are correlated with synaptic strength. 2014, Pubmed

Araya, Activity-dependent dendritic spine neck changes are correlated with synaptic strength. 2014, Pubmed
Araya, Dendritic spines linearize the summation of excitatory potentials. 2006, Pubmed
Bartos, Postsynaptic clustering and activation of Pyk2 by PSD-95. 2010, Pubmed
Béïque, Arc-dependent synapse-specific homeostatic plasticity. 2011, Pubmed
Chen, Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. , Pubmed
Chen, Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. 2014, Pubmed
Chowdhury, Ca²⁺/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down. 2018, Pubmed , Xenbase
Collingridge, Receptor trafficking and synaptic plasticity. 2004, Pubmed
Delaglio, NMRPipe: a multidimensional spectral processing system based on UNIX pipes. 1995, Pubmed
Desai, Critical periods for experience-dependent synaptic scaling in visual cortex. 2002, Pubmed
Diering, PKA-GluA1 coupling via AKAP5 controls AMPA receptor phosphorylation and cell-surface targeting during bidirectional homeostatic plasticity. 2014, Pubmed
Efimova, βIII Spectrin Is Necessary for Formation of the Constricted Neck of Dendritic Spines and Regulation of Synaptic Activity in Neurons. 2017, Pubmed
Ehrlich, Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity. 2004, Pubmed
el-Husseini, Protein palmitoylation: a regulator of neuronal development and function. 2002, Pubmed
El-Husseini, Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering. 2000, Pubmed
El-Husseini, Synaptic strength regulated by palmitate cycling on PSD-95. 2002, Pubmed
Elias, Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins. 2006, Pubmed
Esteban, PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. 2003, Pubmed
Fernandes, Mechanisms of homeostatic plasticity in the excitatory synapse. 2016, Pubmed
Fukata, Local palmitoylation cycles define activity-regulated postsynaptic subdomains. 2013, Pubmed
Fukata, Identification of PSD-95 palmitoylating enzymes. 2004, Pubmed
Fukunaga, The interaction between PSD-95 and Ca2+/calmodulin is enhanced by PDZ-binding proteins. 2005, Pubmed
Gainey, Activity-dependent synaptic GRIP1 accumulation drives synaptic scaling up in response to action potential blockade. 2015, Pubmed
Hayashi, Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. 2000, Pubmed
He, Stabilization of Ca2+-permeable AMPA receptors at perisynaptic sites by GluR1-S845 phosphorylation. 2009, Pubmed
Hell, CaMKII: claiming center stage in postsynaptic function and organization. 2014, Pubmed
Hoeflich, Calmodulin in action: diversity in target recognition and activation mechanisms. 2002, Pubmed
Hou, Homeostatic regulation of AMPA receptor trafficking and degradation by light-controlled single-synaptic activation. 2011, Pubmed
Huganir, AMPARs and synaptic plasticity: the last 25 years. 2013, Pubmed
Joiner, Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling. 2010, Pubmed
Kim, Calcineurin mediates synaptic scaling via synaptic trafficking of Ca2+-permeable AMPA receptors. 2014, Pubmed
Kurokawa, Target-induced conformational adaptation of calmodulin revealed by the crystal structure of a complex with nematode Ca(2+)/calmodulin-dependent kinase kinase peptide. 2001, Pubmed
Lim, Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102. 2002, Pubmed
Malenka, LTP and LTD: an embarrassment of riches. 2004, Pubmed
Masuko, Interaction of NE-dlg/SAP102, a neuronal and endocrine tissue-specific membrane-associated guanylate kinase protein, with calmodulin and PSD-95/SAP90. A possible regulatory role in molecular clustering at synaptic sites. 1999, Pubmed
Matt, HCN2 channels in local inhibitory interneurons constrain LTP in the hippocampal direct perforant path. 2011, Pubmed
Meyer, Calmodulin trapping by calcium-calmodulin-dependent protein kinase. 1992, Pubmed
Micheva, Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers. 2010, Pubmed
Morabito, Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons. 2004, Pubmed
Nair, Super-resolution imaging reveals that AMPA receptors inside synapses are dynamically organized in nanodomains regulated by PSD95. 2013, Pubmed
Nelson, Phosphorylation of threonine-19 of PSD-95 by GSK-3β is required for PSD-95 mobilization and long-term depression. 2013, Pubmed
Noritake, Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95. 2009, Pubmed
O'Brien, Activity-dependent modulation of synaptic AMPA receptor accumulation. 1998, Pubmed
Opazo, CaMKII triggers the diffusional trapping of surface AMPARs through phosphorylation of stargazin. 2010, Pubmed
Ottiger, Measurement of J and dipolar couplings from simplified two-dimensional NMR spectra. 1998, Pubmed
Paarmann, Formation of complexes between Ca2+.calmodulin and the synapse-associated protein SAP97 requires the SH3 domain-guanylate kinase domain-connecting HOOK region. 2002, Pubmed
Pang, Calmodulin controls synaptic strength via presynaptic activation of calmodulin kinase II. 2010, Pubmed
Patriarchi, Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor. 2016, Pubmed
Peineau, LTP inhibits LTD in the hippocampus via regulation of GSK3beta. 2007, Pubmed
Pérez-Otaño, Endocytosis and synaptic removal of NR3A-containing NMDA receptors by PACSIN1/syndapin1. 2006, Pubmed
Pettersen, UCSF Chimera--a visualization system for exploratory research and analysis. 2004, Pubmed
Pratt, Presenilin 1 regulates homeostatic synaptic scaling through Akt signaling. 2011, Pubmed , Xenbase
Rajman, A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses. 2017, Pubmed
Rhoads, Sequence motifs for calmodulin recognition. 1997, Pubmed
Rodriguez, Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. 2008, Pubmed
Sanderson, NMDA Receptor-Dependent LTD Requires Transient Synaptic Incorporation of Ca²⁺-Permeable AMPARs Mediated by AKAP150-Anchored PKA and Calcineurin. 2016, Pubmed
Schlüter, Alternative N-terminal domains of PSD-95 and SAP97 govern activity-dependent regulation of synaptic AMPA receptor function. 2006, Pubmed
Schnell, Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number. 2002, Pubmed
Sdrulla, Double dissociation between long-term depression and dendritic spine morphology in cerebellar Purkinje cells. 2007, Pubmed
Siddoway, An essential role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling. 2013, Pubmed
Singla, Molecular characterization of calmodulin trapping by calcium/calmodulin-dependent protein kinase II. 2001, Pubmed
Sinnen, Optogenetic Control of Synaptic Composition and Function. 2017, Pubmed
Soares, Differential subcellular targeting of glutamate receptor subtypes during homeostatic synaptic plasticity. 2013, Pubmed
Steiner, Destabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity. 2008, Pubmed
Steinmetz, Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. 2016, Pubmed
Sturgill, Distinct domains within PSD-95 mediate synaptic incorporation, stabilization, and activity-dependent trafficking. 2009, Pubmed
Sun, PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down. 2011, Pubmed
Tan, GRIP1 is required for homeostatic regulation of AMPAR trafficking. 2015, Pubmed
Tang, A trans-synaptic nanocolumn aligns neurotransmitter release to receptors. 2016, Pubmed
Thiagarajan, Adaptation to synaptic inactivity in hippocampal neurons. 2005, Pubmed
Tokumitsu, Calcium/calmodulin-dependent protein kinase kinase: identification of regulatory domains. 1997, Pubmed
Turrigiano, Activity-dependent scaling of quantal amplitude in neocortical neurons. 1998, Pubmed
van Zundert, Modeling protein-protein complexes using the HADDOCK webserver "modeling protein complexes with HADDOCK". 2014, Pubmed
Wan, Palmitoylated proteins: purification and identification. 2007, Pubmed
Wang, Independent expression of synaptic and morphological plasticity associated with long-term depression. 2007, Pubmed
Wang, AMPA receptor trafficking in homeostatic synaptic plasticity: functional molecules and signaling cascades. 2012, Pubmed
Wei, Regulation of AMPA receptor trafficking and function by glycogen synthase kinase 3. 2010, Pubmed
Xu, Molecular dissociation of the role of PSD-95 in regulating synaptic strength and LTD. 2008, Pubmed
Yang, Delivery of AMPA receptors to perisynaptic sites precedes the full expression of long-term potentiation. 2008, Pubmed
Yokoi, Identification of PSD-95 Depalmitoylating Enzymes. 2016, Pubmed
Zhang, Structural basis for Ca2+-induced activation and dimerization of estrogen receptor α by calmodulin. 2012, Pubmed , Xenbase
Zhang, Capping of the N-terminus of PSD-95 by calmodulin triggers its postsynaptic release. 2014, Pubmed
Zweckstetter, NMR: prediction of molecular alignment from structure using the PALES software. 2008, Pubmed