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XB-ART-56602
Adv Exp Med Biol 2019 Jan 01;1185:483-487. doi: 10.1007/978-3-030-27378-1_79.
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Prominin-1 and Photoreceptor Cadherin Localization in Xenopus laevis: Protein-Protein Relationships and Function.

Carr BJ , Yang LL , Moritz OL .


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Retinal degenerative diseases are genetically diverse and rare inherited disorders that cause the death of rod and cone photoreceptors, resulting in progressive vision loss and blindness. This review will focus on two retinal degeneration-causing genes: prominin-1 (prom1) and photoreceptor cadherin (prCAD). We will discuss protein localization, potential roles in photoreceptor outer segment disc morphogenesis, and areas for future investigation.

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Species referenced: Xenopus laevis
Genes referenced: prom1