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XB-ART-5781
Curr Biol 2003 Feb 04;133:R96-8. doi: 10.1016/s0960-9822(03)00036-8.
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Organogenesis: making pancreas from liver.



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Making endocrine pancreas cells at will is one of the major goals of cellular based therapies for diabetes. The experimentally induced conversion of hepatocytes into pancreatic cells, using a modified version of the transcription factor Pdx-1, may provide an alternative to stem cell approaches.

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Species referenced: Xenopus laevis
Genes referenced: ttr