XB-ART-59810
Front Endocrinol (Lausanne)
2023 Jan 01;14:1184013. doi: 10.3389/fendo.2023.1184013.
Show Gene links
Show Anatomy links
Cell cycle activation in thyroid hormone-induced apoptosis and stem cell development during Xenopus intestinal metamorphosis.
Tanizaki Y
,
Shibata Y
,
Na W
.
???displayArticle.abstract???
Amphibian metamorphosis resembles mammalian postembryonic development, a period around birth when many organs mature into their adult forms and when plasma thyroid hormone (T3) concentration peaks. T3 plays a causative role for amphibian metamorphosis. This and its independence from maternal influence make metamorphosis of amphibians, particularly anurans such as pseudo-tetraploid Xenopus laevis and its highly related diploid species Xenopus tropicalis, an excellent model to investigate how T3 regulates adult organ development. Studies on intestinal remodeling, a process that involves degeneration of larval epithelium via apoptosis and de novo formation of adult stem cells followed by their proliferation and differentiation to form the adult epithelium, have revealed important molecular insights on T3 regulation of cell fate during development. Here, we review some evidence suggesting that T3-induced activation of cell cycle program is important for T3-induced larval epithelial cell death and de novo formation of adult intestinal stem cells.
???displayArticle.pubmedLink??? 37265708
???displayArticle.pmcLink??? PMC10230048
???displayArticle.link??? Front Endocrinol (Lausanne)
References [+] :
Amano,
Isolation of genes involved in intestinal remodeling during anuran metamorphosis.
1998, Pubmed,
Xenbase
Amano, Isolation of genes involved in intestinal remodeling during anuran metamorphosis. 1998, Pubmed , Xenbase
Amati, Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death. 1994, Pubmed
Bao, Intestinal homeostasis: a communication between life and death. 2020, Pubmed
Bao, Thyroid Hormone Receptor Alpha Mutations Lead to Epithelial Defects in the Adult Intestine in a Mouse Model of Resistance to Thyroid Hormone. 2019, Pubmed
Blitz, Biallelic genome modification in F(0) Xenopus tropicalis embryos using the CRISPR/Cas system. 2013, Pubmed , Xenbase
Buchholz, Molecular and developmental analyses of thyroid hormone receptor function in Xenopus laevis, the African clawed frog. 2006, Pubmed , Xenbase
Buchholz, Dual function model revised by thyroid hormone receptor alpha knockout frogs. 2018, Pubmed , Xenbase
Buchholz, Transgenic analysis reveals that thyroid hormone receptor is sufficient to mediate the thyroid hormone signal in frog metamorphosis. 2004, Pubmed , Xenbase
Buchholz, A dominant-negative thyroid hormone receptor blocks amphibian metamorphosis by retaining corepressors at target genes. 2003, Pubmed , Xenbase
Buchholz, Pairing morphology with gene expression in thyroid hormone-induced intestinal remodeling and identification of a core set of TH-induced genes across tadpole tissues. 2007, Pubmed , Xenbase
Bulynko, Nuclear receptor coactivators: structural and functional biochemistry. 2011, Pubmed
Choi, Growth, Development, and Intestinal Remodeling Occurs in the Absence of Thyroid Hormone Receptor α in Tadpoles of Xenopus tropicalis. 2017, Pubmed , Xenbase
Choi, Unliganded thyroid hormone receptor α regulates developmental timing via gene repression in Xenopus tropicalis. 2015, Pubmed , Xenbase
Clevers, The intestinal crypt, a prototype stem cell compartment. 2013, Pubmed
Dang, c-Myc target genes involved in cell growth, apoptosis, and metabolism. 1999, Pubmed
Denver, Thyroid hormone receptor subtype specificity for hormone-dependent neurogenesis in Xenopus laevis. 2009, Pubmed , Xenbase
Flamant, Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene. 2002, Pubmed
Fu, Thyroid hormone activates Xenopus MBD3 gene via an intronic TRE in vivo. 2020, Pubmed , Xenbase
Fu, Genome-wide identification of thyroid hormone receptor targets in the remodeling intestine during Xenopus tropicalis metamorphosis. 2017, Pubmed , Xenbase
Grimaldi, Mechanisms of thyroid hormone receptor action during development: lessons from amphibian studies. 2013, Pubmed , Xenbase
Harper, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. 2011, Pubmed
Hasebe, Epithelial-connective tissue interactions induced by thyroid hormone receptor are essential for adult stem cell development in the Xenopus laevis intestine. 2011, Pubmed , Xenbase
Hasebe, Thyroid hormone-up-regulated hedgehog interacting protein is involved in larval-to-adult intestinal remodeling by regulating sonic hedgehog signaling pathway in Xenopus laevis. 2008, Pubmed , Xenbase
Hasebe, Thyroid Hormone-Induced Activation of Notch Signaling is Required for Adult Intestinal Stem Cell Development During Xenopus Laevis Metamorphosis. 2017, Pubmed , Xenbase
Hasebe, Thyroid hormone-induced sonic hedgehog signal up-regulates its own pathway in a paracrine manner in the Xenopus laevis intestine during metamorphosis. 2012, Pubmed , Xenbase
Hasebe, Thyroid hormone activates Wnt/β-catenin signaling involved in adult epithelial development during intestinal remodeling in Xenopus laevis. 2016, Pubmed , Xenbase
Heimeier, Studies on Xenopus laevis intestine reveal biological pathways underlying vertebrate gut adaptation from embryo to adult. 2010, Pubmed , Xenbase
Ishizuya-Oka, Origin of the adult intestinal stem cells induced by thyroid hormone in Xenopus laevis. 2009, Pubmed , Xenbase
Ishizuya-Oka, Development of the connective tissue in the digestive tract of the larval and metamorphosing Xenopus laevis. 1987, Pubmed , Xenbase
Ishizuya-Oka, Programmed cell death and heterolysis of larval epithelial cells by macrophage-like cells in the anuran small intestine in vivo and in vitro. 1992, Pubmed , Xenbase
Ishizuya-Oka, Thyroid hormone-upregulated expression of Musashi-1 is specific for progenitor cells of the adult epithelium during amphibian gastrointestinal remodeling. 2003, Pubmed , Xenbase
Ishizuya-Oka, Evolutionary insights into postembryonic development of adult intestinal stem cells. 2011, Pubmed
Ishizuya-Oka, Thyroid hormone regulation of stem cell development during intestinal remodeling. 2008, Pubmed , Xenbase
Ishizuya-Oka, Thyroid-hormone-dependent and fibroblast-specific expression of BMP-4 correlates with adult epithelial development during amphibian intestinal remodeling. 2001, Pubmed , Xenbase
Ishizuya-Oka, Shh/BMP-4 signaling pathway is essential for intestinal epithelial development during Xenopus larval-to-adult remodeling. 2006, Pubmed , Xenbase
Ishizuya-Oka, Thyroid hormone-regulated Wnt5a/Ror2 signaling is essential for dedifferentiation of larval epithelial cells into adult stem cells in the Xenopus laevis intestine. 2014, Pubmed , Xenbase
Ishizuya-Oka, Connective tissue is involved in adult epithelial development of the small intestine during anuran metamorphosis in vitro. 1992, Pubmed
Ishizuya-Oka, Establishment of intestinal stem cell niche during amphibian metamorphosis. 2013, Pubmed , Xenbase
Ishizuya-Oka, Thyroid hormone-induced expression of sonic hedgehog correlates with adult epithelial development during remodeling of the Xenopus stomach and intestine. 2001, Pubmed , Xenbase
Jones, N-CoR-HDAC corepressor complexes: roles in transcriptional regulation by nuclear hormone receptors. 2003, Pubmed , Xenbase
Koskinen, Role of myc amplification and overexpression in cell growth, differentiation and death. 1993, Pubmed
Kress, The frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates beta-catenin signaling in mouse intestine. 2009, Pubmed
Kuchino, Myc-mediated apoptosis. 1996, Pubmed
Lazar, Thyroid hormone receptors: multiple forms, multiple possibilities. 1993, Pubmed
Lei, Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). 2012, Pubmed , Xenbase
Lei, Generation of gene disruptions by transcription activator-like effector nucleases (TALENs) in Xenopus tropicalis embryos. 2013, Pubmed , Xenbase
Marshall, Cell specialization in the epithelium of the small intestine of feeding Xenopus laevis tadpoles. 1978, Pubmed , Xenbase
Matsuda, An essential and evolutionarily conserved role of protein arginine methyltransferase 1 for adult intestinal stem cells during postembryonic development. 2010, Pubmed , Xenbase
McMahon, MYC and the control of apoptosis. 2014, Pubmed
Muncan, Blimp1 regulates the transition of neonatal to adult intestinal epithelium. 2011, Pubmed
Na, Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during Xenopus tropicalis metamorphosis. 2020, Pubmed , Xenbase
Nakade, Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9. 2014, Pubmed , Xenbase
Nakajima, Dual mechanisms governing muscle cell death in tadpole tail during amphibian metamorphosis. 2003, Pubmed , Xenbase
Nakajima, A unique role of thyroid hormone receptor β in regulating notochord resorption during Xenopus metamorphosis. 2019, Pubmed , Xenbase
Nakajima, Thyroid Hormone Receptor α- and β-Knockout Xenopus tropicalis Tadpoles Reveal Subtype-Specific Roles During Development. 2018, Pubmed , Xenbase
Nakayama, Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis. 2013, Pubmed , Xenbase
Nieminen, c-Myc blazing a trail of death: coupling of the mitochondrial and death receptor apoptosis pathways by c-Myc. 2007, Pubmed
Okada, Molecular and cytological analyses reveal distinct transformations of intestinal epithelial cells during Xenopus metamorphosis. 2015, Pubmed , Xenbase
Okada, A balance of Mad and Myc expression dictates larval cell apoptosis and adult stem cell development during Xenopus intestinal metamorphosis. 2017, Pubmed , Xenbase
Okada, The balance of two opposing factors Mad and Myc regulates cell fate during tissue remodeling. 2018, Pubmed , Xenbase
O'Malley, Minireview: nuclear receptor and coregulator proteomics--2012 and beyond. 2012, Pubmed
Packham, c-Myc and apoptosis. 1995, Pubmed
Pelengaris, Action of Myc in vivo - proliferation and apoptosis. 2000, Pubmed
Perissi, Deconstructing repression: evolving models of co-repressor action. 2010, Pubmed
Plateroti, Thyroid hormone receptor alpha1 directly controls transcription of the beta-catenin gene in intestinal epithelial cells. 2006, Pubmed
Plateroti, Functional interference between thyroid hormone receptor alpha (TRalpha) and natural truncated TRDeltaalpha isoforms in the control of intestine development. 2001, Pubmed
Plateroti, Involvement of T3Ralpha- and beta-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development. 1999, Pubmed
Porterfield, The role of thyroid hormones in prenatal and neonatal neurological development--current perspectives. 1993, Pubmed
Sachs, Unliganded thyroid hormone receptor function: amphibian metamorphosis got TALENs. 2015, Pubmed , Xenbase
Sachs, Dual functions of thyroid hormone receptors during Xenopus development. 2000, Pubmed , Xenbase
Schreiber, Remodeling of the intestine during metamorphosis of Xenopus laevis. 2005, Pubmed , Xenbase
Schreiber, Diverse developmental programs of Xenopus laevis metamorphosis are inhibited by a dominant negative thyroid hormone receptor. 2001, Pubmed , Xenbase
Schreiber, Cell-cell interactions during remodeling of the intestine at metamorphosis in Xenopus laevis. 2009, Pubmed , Xenbase
Shi, Biphasic intestinal development in amphibians: embryogenesis and remodeling during metamorphosis. 1996, Pubmed , Xenbase
Shi, Thyroid hormone and intestinal tumor: a Wnt connection. 2018, Pubmed
Shi, The earliest changes in gene expression in tadpole intestine induced by thyroid hormone. 1993, Pubmed , Xenbase
Shi, Thyroid hormone receptor actions on transcription in amphibia: The roles of histone modification and chromatin disruption. 2012, Pubmed
Shi, Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas. 1992, Pubmed
Shi, Heritable CRISPR/Cas9-mediated targeted integration in Xenopus tropicalis. 2015, Pubmed , Xenbase
Shi, Life Without Thyroid Hormone Receptor. 2021, Pubmed , Xenbase
Shi, The development of the adult intestinal stem cells: Insights from studies on thyroid hormone-dependent amphibian metamorphosis. 2011, Pubmed , Xenbase
Shi, Dual functions of thyroid hormone receptors in vertebrate development: the roles of histone-modifying cofactor complexes. 2009, Pubmed , Xenbase
Shibata, Thyroid Hormone Receptor Is Essential for Larval Epithelial Apoptosis and Adult Epithelial Stem Cell Development but Not Adult Intestinal Morphogenesis during Xenopus tropicalis Metamorphosis. 2021, Pubmed , Xenbase
Shibata, Organ-Specific Requirements for Thyroid Hormone Receptor Ensure Temporal Coordination of Tissue-Specific Transformations and Completion of Xenopus Metamorphosis. 2020, Pubmed , Xenbase
Shibata, Thyroid hormone receptor beta is critical for intestinal remodeling during Xenopus tropicalis metamorphosis. 2020, Pubmed , Xenbase
Sirakov, Thyroid hormones and their nuclear receptors: new players in intestinal epithelium stem cell biology? 2014, Pubmed
Sterling, Cytological and morphological analyses reveal distinct features of intestinal development during Xenopus tropicalis metamorphosis. 2012, Pubmed , Xenbase
Stolow, Xenopus sonic hedgehog as a potential morphogen during embryogenesis and thyroid hormone-dependent metamorphosis. 1995, Pubmed , Xenbase
Sun, Epigenetic regulation of thyroid hormone-induced adult intestinal stem cell development during anuran metamorphosis. 2014, Pubmed , Xenbase
Sun, Thyroid hormone regulation of adult intestinal stem cell development: mechanisms and evolutionary conservations. 2012, Pubmed , Xenbase
Tanizaki, Analysis of Thyroid Hormone Receptor α-Knockout Tadpoles Reveals That the Activation of Cell Cycle Program Is Involved in Thyroid Hormone-Induced Larval Epithelial Cell Death and Adult Intestinal Stem Cell Development During Xenopus tropicalis Metamorphosis. 2021, Pubmed , Xenbase
Tata, Gene expression during metamorphosis: an ideal model for post-embryonic development. 1993, Pubmed
Thompson, The many roles of c-Myc in apoptosis. 1998, Pubmed
Tsai, Molecular mechanisms of action of steroid/thyroid receptor superfamily members. 1994, Pubmed
van der Flier, Stem cells, self-renewal, and differentiation in the intestinal epithelium. 2009, Pubmed
Wang, Developmental regulation and function of thyroid hormone receptors and 9-cis retinoic acid receptors during Xenopus tropicalis metamorphosis. 2008, Pubmed , Xenbase
Wang, Targeted gene disruption in Xenopus laevis using CRISPR/Cas9. 2015, Pubmed , Xenbase
Wen, Thyroid Hormone Receptor α Controls Developmental Timing and Regulates the Rate and Coordination of Tissue-Specific Metamorphosis in Xenopus tropicalis. 2017, Pubmed , Xenbase
Wen, Unliganded thyroid hormone receptor α controls developmental timing in Xenopus tropicalis. 2015, Pubmed , Xenbase
Wen, A requirement for hedgehog signaling in thyroid hormone-induced postembryonic intestinal remodeling. 2015, Pubmed , Xenbase
Wen, Regulation of growth rate and developmental timing by Xenopus thyroid hormone receptor α. 2016, Pubmed , Xenbase
Yen, Physiological and molecular basis of thyroid hormone action. 2001, Pubmed
Young, Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. 2011, Pubmed , Xenbase