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XB-ART-929
Cell 2005 Dec 16;1236:982-4. doi: 10.1016/j.cell.2005.11.028.
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Bmp signaling: turning a half into a whole.

Kimelman D , Pyati UJ .


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In a famous experiment over a century ago, Hans Spemann demonstrated that amphibians have a remarkable ability to compensate for perturbations to the embryo. In this issue of Cell, Reversade and De Robertis (2005) uncover the basis of this phenomenon. They demonstrate that interactions between bone morphogenetic proteins (Bmps) and their inhibitors on both the dorsal and ventral sides of the early Xenopus embryo are involved in creating the body plan.

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References :
Reversade, Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field. 2005, Pubmed, Xenbase