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XB-ART-9880
Curr Biol 2000 Nov 16;1022:R843-6. doi: 10.1016/s0960-9822(00)00789-2.
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Vertebrate development: the fast track to nodal signalling.



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The transcription factors Fast-1 and Mixer are important terminal components of Smad2-mediated TGF-beta signal transduction. Recent studies demonstrate that Fast-1 and Mixer play critical roles in the formation of endoderm and dorsal mesoderm in zebrafish.

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Species referenced: Xenopus
Genes referenced: mixer nodal nodal1 smad2