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Antibody Name: Hspa5 Ab3 Common Name: Anti-GRP78 BiP RRID: Synonyms: ab32618, anti-BiP, anti-grp78 Antigens Gene: hspa5 Clone Type: Polyclonal Source: Abcam

Antibody
Clone Number
Purification
Isotype	isotype unknown
Host Organism	rabbit
Xenopus Reactivity	X. tropicalis, X. laevis
Non-Xenopus Reactivity	chicken, human, monkey, rat
Description:	hspa5 (aka grp78) is a heat shock protein: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate. Supplied by Abcam
Immunogen
Name	hspa5
Type	polypeptide
Post Translational Modifications	unknown post translational modifications
Source Organism	rabbit
Description	corresponding to amino acids 24-43 of Human GRP78 BiP. Cellular localization Endoplasmic reticulum lumen. Melanosome. Cytoplasm.
Sequence
Reported Usage
chromatin immunoprecipitation	1:200 dilution
Publications
???displayAntibody.papersFirst???	Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosa., J Neurosci 2014
???displayAntibody.papersRecent???	Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER., Cell Rep 2022
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