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XB-ANTIBODY-17328315
Antibody Name:
Mbp Ab2
Common Name: ab92406 RRID: Synonyms: xmbp.1
Source: |
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Antibody | |
Clone Number | 12 |
Purification | |
Isotype | IgG |
Host Organism | rat |
Xenopus Reactivity | X. tropicalis, X. laevis |
Non-Xenopus Reactivity | cow, human, mouse, pig, rabbit, rat |
Description: | The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. Abcam |
Immunogen | |
Name | myelin basic protein |
Type | synthetic sequence |
Post Translational Modifications | unknown post translational modifications |
Source Organism | frog |
Description | ab92406 reacts weakly with peptides ending in the Phe 91 where the 91-92 Phe-Phe bond is broken. Synthetic peptide 82-99 reacts very well, as does intact MBP. Further epitope analysis indicates binding to a region defined by amino acids 82-87. |
Sequence | |
Reported Usage | |
immunohistochemistry | |
Publications | |
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Astrocytes phagocytose focal dystrophies from shortening myelin segments in the optic nerve of Xenopus laevis at metamorphosis., Proc Natl Acad Sci U S A 2015 |
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