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XB-ANTIBODY-29208978
Antibody Name:
h3-3a Ab43
Common Name: H3K27me3 RRID: AB_2943245 Synonyms: Tri-Methyl-Histone H3 (Lys27)
Source: Cell Signaling Technology |
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Antibody | |
Clone Number | C36B11 |
Purification | |
Isotype | IgG |
Host Organism | rabbit |
Xenopus Reactivity | X. laevis |
Non-Xenopus Reactivity | human, monkey, mouse, rat |
Description: | Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb detects endogenous levels of histone H3 only when tri-methylated on Lys27. The antibody does not cross-react with non-methylated, mono-methylated or di-methylated Lys27. In addition, the antibody does not cross-react with mono-methylated, di-methylated or tri-methylated histone H3 at Lys4, Lys9, Lys36 or Histone H4 at Lys20. |
Immunogen | |
Name | h3-3a K27me3 |
Type | synthetic sequence |
Post Translational Modifications | Methylated |
Source Organism | Other |
Description | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of histone H3 in which Lys27 is tri-methylated. |
Sequence | |
Reported Usage | |
chromatin immunoprecipitation | |
Publications | |
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BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Sci Adv 2019 |
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