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XB-MORPHOLINO-17249641
Morpholino Name:
gnas MO1
Synonyms: Gnas-MO
Target mRNA: gnas
Morpholino Type: uncategorized morpholino
Sequence: 5' AGACACCCCATGGTCCGTGTGGGCT 3'
Source: Gene Tools LLC
Synonyms: Gnas-MO
Target mRNA: gnas
Morpholino Type: uncategorized morpholino
Sequence: 5' AGACACCCCATGGTCCGTGTGGGCT 3'
Source: Gene Tools LLC
Target mRNA | tropicalis | laevis.L | laevis.S | ||||
Identities | 22/25 | 25/25 | 25/25 | ||||
genome
MO
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5' CGCCCGCCCGGACCATGGGGTGTCT 3' |||| | ||||||||||||||||| 3' TCGGGTGTGCCTGGTACCCCACAGA 5' |
5' AGCCCACACGGACCATGGGGTGTCT 3' ||||||||||||||||||||||||| 3' TCGGGTGTGCCTGGTACCCCACAGA 5' |
5' AGCCCACACGGACCATGGGGTGTCT 3' ||||||||||||||||||||||||| 3' TCGGGTGTGCCTGGTACCCCACAGA 5' |
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Genomic Alignments | Position | Identity | Strand | Target | Target mRNA | ||
laevis 10.1 | Chr9_10L:16542246..16542270 | 25/25 | Sense | target | gnas.L | ||
Chr9_10S:15786048..15786072 | 25/25 | Sense | target | gnas.S | tropicalis 10.0 | Chr10:2999975..2999999 | 22/25 | Antisense | target | gnas |
Chr4:93784896..93784920 | 22/25 | Sense | off-target | cyp4b1 | |||
Publications | |||||||
???morpholino.displaySummary.papersFirst??? |
Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros., Dev Biol 2013 |
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???morpholino.displaySummary.papersRecent??? |
Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Development 2018 |
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???morpholino.displaySummary.papersAll??? |